Does in utero exposure to heavy maternal smoking induce nicotine withdrawal symptoms in neonates?

Maternal drug use during pregnancy is associated with fetal passive addiction and neonatal withdrawal syndrome. Cigarette smoking-highly prevalent during pregnancy-is associated with addiction and withdrawal syndrome in adults. We conducted a prospective, two-group parallel study on 17 consecutive newborns of heavy-smoking mothers and 16 newborns of nonsmoking, unexposed mothers (controls).

[Congenital toxoplasmosis and seroconversion at the end of pregnancy: clinical observations].

We report seven cases of subclinical congenital toxoplasmosis secondary to maternal primary infections. Mothers were infected between two and four weeks prior to delivery. The diagnostic criteria of congenital infections included: IgM antibody (Ab) (1 case); IgM and IgA Ab (1 case); a real IgG seroconversion in the neonatal and postnatal samples (3 cases); persistence of IgG Ab beyond 6 months post-delivery (2 cases).

Atypical lymphohistiocytic bone tumour (osseous variant of Rosai-Dorfman disease?).

A single osteolytic bone tumour with a cellular composition similar to that of the extra-nodal localization of Sinus Histiocytosis with Massive Lymphadenopathy although with greater cellular atypicality is described. This histological similarity suggests the possible occurrence of isolated bone involvement of Rosai-Dorfman disease, with atypical cytology but benign evolution, which has not been reported in the literature.

The therapeutic efficacy of human immunoglobulins as a function of their in vitro antibody activity toward circulating antigens in children with recurrent infections of the upper respiratory tract.

Children with recurrent infections of the upper respiratory tract were treated by injections of human immunoglobulins. Of the 58 children who were followed after treatment, the clinical outcome and the results of laboratory tests, i.e.

beta+-Thalassaemia, Haemoglobin S and Hereditary elliptocytosis in a Zairian Family. Ischaemic costal necroses in a child with sickle cell beta+-Thalassaemia.

In a family of Low-Zaïre, a child with sickle cell beta+-thalassaemia disease, aged 7, presented 33.6% haemoglobin A. The clinical evolution was benign, except for the occurrence of an extensive bilateral ischemic necrosis of the ribs.