Publications by authors named "Fiali Lack"

Background: Urogenital schistosomiasis is endemic in Togo. Since 2010, Togo has used preventive chemotherapy to control the disease and periodically assess its impact. This study aimed to estimate the prevalence of urogenital schistosomiasis and identify associated risk factors among school-age children in three districts of the Plateaux Region of Togo.

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Objective: To provide an up-to-date data, we aim to estimate the frequency of sickle cell disease among children in the pediatric clinics of the Sylvanus Olympio University Hospital, Lome, Togo, in 2022.

Results: A total of 317 children with a median age of 8 years (Interquartile range: 4-12) were included. Both parents knew their Hb phenotype in 7.

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Introduction: The diagnosis of superficial cutaneous mycosis (SCM) is very frequently evoked during dermatological consultations in tropical zones, but mycological confirmation is very rarely performed routinely. The aim of this study is to describe the profile of fungal species encountered during dermatology consultations in Lomé (Togo), to establish their relative frequencies and, above all, to discuss their responsibility in the lesions observed.

Method: This was a descriptive study carried out from February 2020 to March 2022, involving patients presenting lesions suspected of MCS, seen in dermatological consultations.

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Article Synopsis
  • Tinea capitis is a fungal infection common in children, and this study aimed to determine its prevalence among schoolchildren in Lomé, Togo, along with identifying the fungi involved and the related risk factors.
  • A cross-sectional study was conducted with 15,087 pupils, revealing a prevalence of 3.08% for tinea capitis, primarily caused by Trichophyton mentagrophytes.
  • The research identified risk factors such as living with pets, infrequent bathing, previous ringworm infections, sharing hygiene items, and having similar lesions in the same household, indicating a need for targeted preventive measures.
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Background: Due to the burden of schistosomiasis (SCH) and soil-transmitted helminths (STH), Togo Ministry of Health launched a program for Preventive Chemotherapy Neglected Tropical Diseases (PC-NTDs) in 2009, initiating integrated mass drug administration (MDA) the following year for the three PC-NTDs: SCH, STH and onchocerciasis. Significant reduction of infection across the country was noted in 2015 during the first impact assessment, following 5 years of high-coverage MDA implemented at the sub-district level for SCH and district level for STH. After another 5 years of effective MDA, a second survey was conducted in 2021 to re-evaluate the situation of SCH and STH.

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Article Synopsis
  • The study aimed to determine how common malaria and Covid-19 are among febrile patients in Lomé, using various testing methods over two months in 2020.
  • A total of 243 patients were tested, revealing a malaria prevalence of about 25%, while the presence of SARS-CoV-2 was found in approximately 7.4% of the participants.
  • The findings suggest that there may be cross-reactivity between Covid-19 and malaria in rapid tests, indicating the need for PCR testing to accurately diagnose Covid-19 in areas where malaria is common.
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Background: Over the years, the focus of infectious diseases in many African countries has been mainly on viral, bacterial and parasitic infections. Serious fungal infections (SFIs) with comparable morbidity rate in these countries remain neglected.

Objectives: To estimate the burden of SFI in Togo and to stimulate efforts for improved attention.

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Objective: Evaluate the potential effectiveness of the implementation of dolutegravir (DTG)-based regimens in patients on failing current antiretroviral treatment (ART) given the high levels of nucleoside reverse transcriptase inhibitor (NRTI) resistance in Togo.

Design: Patients on ART attending health facilities for routine follow-up visits and for whom HIV viral load test was performed were consecutively included.

Methods: Protease, reverse transcriptase and integrase fragments were sequenced and analyzed for presence of drug resistance mutations for patients with viral load more than 1000 copies/ml.

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