Association of Nicotine Use Disorder with Neurexin 3 Gene Polymorphisms.

Objective: In this study, we aimed to investigate the Neurexin 3 gene (NRXN3) polymorphisms in the rs 221473, rs 221497, rs1004212 and rs11624704 regions in relation to nicotine use disorder (NUD) in the Turkish population.

Method: Power analysis indicated that the NUD group and the control group of this study should each comprise 200 participants in the 18-65 year age range. The NUD group consisted of individuals without a psychiatric first axis disorder except for NUD, mental retardation, past head trauma or a neurological disorder, who had smoked minimally10 cigarettes per day for at least 1 year.

Association of Nicotine Use Disorder with Neurexin 3 Gene Polymorphisms.

Objective: In this study, we aimed to investigate the Neurexin 3 gene (NRXN3) polymorphisms in the rs 221473, rs 221497, rs1004212 and rs11624704 regions in relation to nicotine use disorder (NUD) in the Turkish population.

Method: Power analysis indicated that the NUD group and the control group of this study should each comprise 200 participants in the 18-65 year age range. The NUD group consisted of individuals without a psychiatric first axis disorder except for NUD, mental retardation, past head trauma or a neurological disorder, who had smoked minimally10 cigarettes per day for at least 1 year.

Role of Oxidative Stress in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.

Objectives: To investigate the role of oxidative stress on pseudoexfoliation formation and progression from pseudoexfoliation syndrome (XFS) to pseudoexfoliation glaucoma (XFG).

Materials And Methods: This study investigated oxidative stress biomarkers in blood samples from 58 patients with XFG, 47 patients with XFS, and 134 healthy age- and sex-matched controls.

Results: The highest serum malondialdehyde (MDA) levels were measured in XFG patients (p<0.

[The Effect of Chronic Cigarette Use on Cognitive Function].

Objective: In this study, we aimed to investigate the effect of chronic cigarette smoking on the cognitive function in people who have no other mental or physical illness other than tobacco use disorder.

Method: The study was carried out on three groups: smokers (n = 71), former smokers (n = 39), and non-smokers (n = 49). The Wisconsin Card Sorting Test (WCST), Stroop Color and Word Test (ST), Trail Making Test (TMT), Auditory Verbal Learning Test (AVLT), and Serial Digit Learning Test (SDLT) were applied to the 3 groups participating in the study.

Carotid intima-media thickness and elastic properties of aortas in normotensive children of hypertensive parents.

A significant correlation between hypertension history and high blood pressure has been observed with regard to age, race and gender. Investigating carotid intima-media thickness and aortic stiffness prior to the development of hypertension in children of hypertensive parents enabled us to evaluate these patients for subclinical atherosclerosis. We compared carotid intima-media thickness, aortic strain, distensibility, stiffness indices and elastic modulus in 67 normotensive children whose parents had a diagnosis of essential hypertension and 39 normotensive children with no parental history of hypertension.

Meta analysis of studies about breast self examination between 2000-2009 in Turkey.

Aim: The aim of this study was to analyze studies in Turkey about self-breast examination and produce conclusive, reliable and detailed basis for future studies.

Methods: Studies performed between 2000 and 2009 (until the end of September) were retrieved from databases using breast cancer, breast examination, breast cancer screening and risk factors as key words. Fifty-nine studies were identified and 18 of them (15 journal articles and three theses) were used for the meta-analysis t.

Effects of various agents on DNA fragmentation and telomerase enzyme activities in adenocarcinoma cell lines.

Natural compounds such as resveratrol, tannic acid, and quercetin may help to treat cancer. Tamoxifen is a non-steroidal anti-estrogen drug widely used in the treatment of patients with estrogen receptor-positive breast cancer. The aim of the study was to compare the effects of these natural compounds and tamoxifen in colon adenocarcinoma (CaCo-2) and breast adenocarcinoma (MCF-7) cell lines, on telomerase enzyme activity, cell viability, number of cells and DNA fragmentation.