Active Video Games Using Virtual Reality Influence Cognitive Performance in Sedentary Female University Students: A Randomized Clinical Trial.

Background: Virtual reality (VR) is an emerging technology that is proving to be effective in encouraging physical activity (PA) and improving health. Although regular PA has many advantages, physical inactivity continues to be a significant global health concern. Using an ActivPAL for PA assessment, this study examines the effects of an active video game (AVG) using VR on cognitive function among female university students.

Perceived Health Needs, Social Support, and Depression Among Patients with Myocardial Infarction: A Cross-Sectional Study.

Background: Cardiovascular diseases are the leading cause of mortality globally. Myocardial infarction (MI), a major type of cardiovascular disease, presents long-term challenges for patients. Recognizing patients' perceived health needs and the factors that influence them is crucial for providing comprehensive care and improving outcomes.

Unraveling the threads of depressive symptoms: Enhancing predictions of depression among university junior students.

Background: The mental burden faced by university students in their early years is not frequently reported in the literature.

Objectives: The aim of this study is to investigate the prevalence and predictors of depression among preparatory (first) year university students using a predictive test developed from general health and well-being questionnaires.

Methods: A cross-sectional study was conducted among university students in the eastern region of Saudi Arabia from March 2023 to June 2023.

Effects of Radiotherapy Alone Versus Concomitant Radiotherapy With Temozolomide Chemotherapy on the Outcome of IDH-wildtype Glioblastoma Patients.

Background: Isocitrate dehydrogenase [IDH]-wildtype glioblastoma is an aggressive brain cancer associated with high recurrence and poor overall survival.

Aim: Our study aims to explore the prognostic effects of radiotherapy [RT] alone versus concomitant RT with temozolomide [TMZ].

Methods: A multicentre retrospective study included a cohort of 244 patients diagnosed with IDH-wildtype glioblastoma, and it was analysed from 2013 to 2020.

Comparative analysis of antifungal activity of Rhazya stricta ethanolic extracts and biogenic silver nanoparticles against pathogenic fungi.

Rhazya stricta, a perennial shrub native to the Middle East and South Asia, has been used in traditional medicine for various therapeutic purposes, including antimicrobial action. The current study aimed to compare the antifungal properties of 96% and 50% ethanolic extracts of R. stricta leaves and their biogenic silver nanoparticles (AgNPs).

Burnout Among Primary Healthcare Nurses: A Study of Association With Depression, Anxiety and Self-Efficacy.

Burnout is a significant issue among healthcare professionals, particularly nurses, due to high workloads and emotional demands. However, limited research has explored burnout among primary healthcare nurses in Saudi Arabia, who play a vital role in healthcare delivery. This study aims to address this gap by investigating burnout levels and their association with anxiety, depression and self-efficacy among primary healthcare nurses.

Predictors to Poor Quality of Life Among Patients with Heart Failure and Its Correlation with Their Medication Adherence: Finding for Healthcare Improvement and Follow-Up.

Background: Understanding medication adherence and its relationship with quality of life (QoL) is essential for improving health outcomes in patients with heart failure (HF).

Objective: This study aimed to investigate the predictors of poor quality of life and its relationship with medication adherence among patients with heart failure.

Methods: A cross-sectional correlational study was performed on 229 patients with HF receiving care at the Cardiac Center of King Salman Specialist Hospital from March to June 2024.

Reliability of clinical examination for the assessment of obstetric anal sphincter injuries. A comparative study with 3D endoanal ultrasonography.

Objective: Anal incontinence (AI) affects up to 40% of women who sustained obstetric anal sphincter injuries (OASIs) due to persistent defects after primary repair or undiagnosed lesions. Aim of our research was to assess the reliability of clinical assessment of OASIs at the delivery as compared to three-dimensional endoanal ultrasonography (3D-EAUS).

Methods: An observational prospective study was conducted between December 2015 and December 2022.

Spectrofluorimetric Determination of 7-Aminoclonazepam, a Major Clonazepam Metabolite, in Human Urine: A Factorial Design of Experiment Approach to Optimize Method Development.

Clonazepam, a high-potency benzodiazepine widely prescribed for seizure and panic disorders, carries a risk of abuse and dependency. This study developed a sensitive and selective spectrofluorimetric method for determining 7-aminoclonazepam, the major metabolite of clonazepam, in human urine. A 2 factorial design was employed to screen the optimal conditions for derivatization with NBD-Cl as the fluorescent label, considering factors such as pH, reagent volumes, temperature, and reaction time.

Investigating the association between resilience and impostor syndrome in undergraduate nursing and medical students: a cross-sectional study.

Impostor syndrome is prevalent among undergraduate nursing and medical students. Resilience is the ability to adapt and rebound from challenges, which is crucial for student well-being and academic success. Exploring the connection between impostor syndrome and resilience is essential to support students effectively.

Nurses' Knowledge Regarding Incontinence-Associated Dermatitis.

Background And Objective: Incontinence-associated dermatitis (IAD), is a skin injury brought on by protracted exposure to urine or feces in the gluteal, sacral, or perianal regions. Therefore, this study aimed to evaluate nurses' level of knowledge, attitudes, social pressure, and intention to prevent IAD and to explore the factors that explain nurses' intention to prevent incontinence-associated dermatitis.

Methods: A cross-sectional study was conducted among staff nurses from two designated hospitals in Riyadh, Saudi Arabia.

Effect of daily immersion of different beverages on the surface roughness and color stability of 3D-printed denture base resins.

Purpose: To measure the effect of daily immersion in varying beverages (distilled water, tea, carbonated beverage, and orange juice) on surface roughness and color stability of 3D-printed denture base resins.

Materials And Methods: 160 acrylic resin discs (15 × 2.5 mm) were made from heat-polymerized (HP), and 3D-printed resins (FormLabs, ASIGA, and NextDent).

Quality of Life and Health Awareness Among Patients With Hypertension in Urban and Rural Regions of Riyadh City, Saudi Arabia.

Background: Hypertension is a leading global health issue and a major risk factor for cardiovascular diseases. Understanding the differences in quality of life (QoL) and health awareness among hypertensive patients in urban and rural regions is critical for developing targeted interventions to improve health outcomes. This study aims to assess the health-related quality of life (HRQoL) and health awareness among hypertensive patients in Riyadh, Saudi Arabia.

Fluorometric detection of quinolones via AIE and FRET with terbium-doped carbon dots and copper nanoclusters.

Terbium and nitrogen co-doped carbon dots (Tb@N-CDs), combined with α-lipoic acid-functionalized copper nanoclusters (LA@CuNCs), were proposed for the ratiometric detection of quinolone (QA) antibiotics. In this system, Tb@N-CDs facilitate the aggregation of LA@CuNCs, enhancing its fluorescence emission at 670 nm via aggregation-induced emission enhancement (AIEE). Meanwhile, the fluorescence emission of Tb@N-CDs at 460 nm diminishes due to Förster resonance energy transfer (FRET).

Healthcare workers' knowledge and preparedness for unprecedented foodborne botulism outbreak in Saudi Arabia.

Background: The recent unprecedented foodborne botulism outbreak in Saudi Arabia necessitated an assessment of healthcare workers' (HCWs) knowledge, attitudes, and practices (KAP). This study assessed healthcare workers' knowledge regarding the transmission, contagiousness, presentation, and diagnosis of foodborne botulism, as well as their management practices, including contacting public health authorities, administering antitoxin, preparedness to respond to botulism cases and consulting generative Artificial Intelligent (AI)-chatbots, like ChatGPT.

Methods: A cross-sectional online survey targeting Saudi HCWs was conducted from May 6-19, 2024, following the first foodborne botulism outbreak.

Seroprevalence of in Cattle in Southern Egypt: Do Milk and Serum Samples Tell the Same Story?

is an intracellular protozoan parasite of veterinary and public health importance. Infection may lead to abortion in susceptible pregnant animals and women, and potentially fatal health complications in immunocompromised individuals. In this study, we aimed to provide an update on the seroprevalence of, and risk factors for, antibodies in cattle from Qena, southern Egypt.

Translation, Cultural Adaptation, and Validation of the Arabic Version of the Student Evidence-Based Practice Questionnaire (S-EBPQ)".

Background: Evidence-based practice (EBP) lowers costs, guarantees staying current with new technology and abilities, and enables the provision of high-quality care. Evidence-based practice (EBP) considered the foundation for safe patient care.

Aim: is to validate and carry out the linguistic-cultural adaptation of the S-EBPQ for the Arabic language.

The Prevalence of Transfusion-Transmitted Infections and Nucleic Acid Testing Among Blood Donors in Makkah, Saudi Arabia.

Background: Despite saving a vast number of lives through blood transfusions, transfusion-transmitted infections (TTIs) still threaten the lives of people needing blood transfusion. Hence, screening blood donors and reviewing the prevalence of TTIs amongst blood donors might show the impact of these infections among our people. The aim of this study was to evaluate the prevalence rates of transfusion-transmitted infections among blood donors in Makkah as foundation for providing harmless blood transfusion in Makkah, Saudi Arabia.

Association of thyroid hormones with the severity of chronic kidney disease: a cross-sectional observational study at Tabuk, Saudi Arabia.

Background: The interplay between chronic kidney disease (CKD) and thyroid dysfunction is becoming more evident in the biomedical community. However, the intricacies of their relationship warrant deeper investigation to understand the clinical implications fully.

Objective: This study aims to systematically evaluate the correlation between thyroid hormone levels, including thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4), and markers of renal disease severity.

Self-medication practices among university students at a public university in Riyadh, Saudi Arabia.

Background: Self-medication is a concern at the global level. It comes with complications and different health issues. This study measures the prevalence, influential factors, and reasons behind self-medication.

Surgical Intervention Outcome for Patients With Acute Vision Loss Due to Allergic Fungal Rhinosinusitis: A Systematic Review and Meta-Analysis.

Allergic fungal rhinosinusitis (AFRS) is a severe type of chronic rhinosinusitis (CRS) characterized by a high risk of acute vision loss resulting from the affection of optic nerves. This vision loss results from direct pressure upon the optic nerve by the sinus tissues and bone degradation. This is why early involvement of a professional is significant so as not to result in a permanent disability.

Developing a switch "OFF-ON" fluorescent probe for detection of melamine based on doubly-protected red emissive copper nanoclusters mediated by Hg ions.

Melamine, often used as an adulterant in infants' formula due to its high protein content, can be harmful when ingested in large amounts, leading to the formation of cyanurate-melamine co-crystals in infants and potentially causing kidney damage. In this study, we introduce a fluorescent method for the selective and reliable detection of melamine in milk and infants' formula. The fluorescent probe comprises copper nanoclusters (Cu NCs) functionalized with thiosalicylic acid (TSA) and polyvinylpyrrolidone (PVP) as double-protecting ligands.

The use of thoracolumbar spinal orthosis in thoracolumbar fractures.

Background: Thoracolumbar fractures are classified into four categories according to the mechanism of injury and fracture morphology into compression fracture, burst fracture, flexion-distraction injury, and fracture dislocation. Unfortunately, the management of spinal fracture has lacked standardization given the many unanswered yet relevant questions regarding the outcome. However, management is generally divided into surgical and nonsurgical treatment such as orthosis.