Publications by authors named "Fethi Ahmet Ozdemir"

In this research, the study utilized the root, leaf, and petiole parts of in vitro grown Salvia hispanica plants as explants. Following UV-C treatment applied to developing callus, methanol extracts were obtained and analyzed using liquid chromatography-mass spectrometry (LC/MS) to investigate their anticancer properties. First, the seeds of S.

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Soil salinization is a serious concern across the globe that is negatively affecting crop productivity. Recently, biochar received attention for mitigating the adverse impacts of salinity. Salinity stress induces osmotic, ionic, and oxidative damages that disturb physiological and biochemical functioning and nutrient and water uptake, leading to a reduction in plant growth and development.

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In recent years, polyhydroquinolines have gained much attention due to their widespread applications in medicine, agriculture, industry, Here, we synthesized a series of novel hydrazone-based polyhydroquinoline derivatives multi-step reactions. These molecules were characterized by modern spectroscopic techniques (H-NMR, C NMR, and LC-HRMS) and their antibacterial and α-glucosidase inhibitory activities were assessed. Compound 8 was found to be the most active inhibitor against NCTC 5348, IM 622, , and ATCC 6337 with a zone of inhibition of 15.

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Pear pomace, a byproduct of juice production, represents a valuable reservoir of bioactive compounds with potential health benefits for humans. This study aimed to evaluate the influence of drying method and temperature on pear pomace, specifically focusing on the drying kinetics, grinding characteristics, color, phenolic profile (LC-MS/MS), and antioxidant activities of the powder. Drying using the contact method at 40 °C with microwave assistance demonstrated the shortest duration, whereas freeze-drying was briefer compared to contact-drying without microwave assistance.

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The effects of water and ethanolic (40 %, 70 %, and 96 %) extraction on the Rhodiola rosea L. phytochemical profile (HPLC analysis), stability during extract drying, potential bioaccessibility in simulated gastric and intestinal conditions, and cytotoxic activity against human colorectal adenocarcinoma cells (Caco-2 and HT-29 cell lines) were investigated. The phytochemical profile, extractability, and stability during extract processing depend on the solvent type.

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Palynological characterization is considered to be one of the significant taxonomic tools for the delimitation and identification of morphologically complicated taxa. Hence, the pollen morphology of 12 species of spineless Astragalus L. was examined using light and scanning electron microscopy.

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The effects of convection drying, freezing, and freeze-drying, on phytochemicals content, in vitro activity and bioaccessibility of sweet basil, cinnamon basil, red rubin basil, and lemon basil were investigated. For evaluation of bioaccessibility, rosmarinic acid content, phenolic content, and antioxidant potential of samples before and after gastric and intestinal steps of digestion were determined. Results showed that the content, activity and bioaccessibility of basil phytochemicals varied depending on the cultivar as well as the applied postharvest preservation.

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Andrographolide (ANDRO), a bitter diterpene lactone found in (Burm.f.) Nees, possesses several biological effects such as antioxidant, anti-inflammatory, and organo-protective effects.

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In classification and identification of plant species, palyno morphological character has remain helpful for plant taxonomist. The aim to investigation this study was to identify the characteristic features of Asteraceae and Poaceae family member collected from lower Himalayas of Pakistan. Light microscope and Scanning electron microscope were used for feature study of allergenic pollen.

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Palyno-anatomical characterization of some selected species of Boraginaceae and Fabaceae using light microscopy (LM) and scanning electron microscopy (SEM) was conducted. Six species of them belongs to four genera of family Boraginaceae and other six species belongs to four genera of Fabaceae. The current study aimed to investigate palyno-anatomical features for correct identification and taxonomic significance.

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Due to increase in energy catastrophe and accompanying environmental issues, the search for renewable and alternative energy resources is a fiercely disputed problem in the scientific world. Biodiesel has proven to be the finest sustainable alternative to gasoline. Because of their environment-friendly character and cost-effectiveness, nonedible oil-bearing seeds could be the possible resource for biodiesel production.

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Article Synopsis
  • - Daidzein is a phytoestrogen found in soybeans that mimics mammalian estrogens and can influence estrogen-related diseases like breast cancer and osteoporosis.
  • - In addition to its estrogen-related benefits, daidzein also acts as an antioxidant and anti-inflammatory agent, which may contribute to its potential anticancer properties.
  • - This review focuses on the pharmacodynamics of daidzein and its implications for human health, especially in alleviating postmenopausal symptoms and offering anti-aging benefits.
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The genus Acacia (Family Leguminosae) is composed of several medicinal plants used for treating miscellaneous diseases. Amid the important members of this genus, A. nilotica and A.

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In current study, 22 herbaceous plant specimens have been examined with the help of light microscope to carry out leaf epidermal anatomy. Foliar micro-morphology of herbaceous plants from Tilla Jogian, Jhelum Pakistan was held first time. The plants were collected from different parts of Tilla Jogian at different elevations.

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Date palm (Phoenix dactylifera L.) is an important traditional crop having socioeconomic values. To best of literature review and our knowledge, there is a gap of taxonomic study on the role of morpho-anatomical features of date palm for correct identification of its varieties.

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The current research work was aimed to determine the morphological variation in the seeds of subfamilies Caesalpinioideae, Mimosoideae, and Papilionoideae using scanning electron microscope to investigate the different seed features including; Seed length, width, weight, hilum shape, position, fracture line pattern, pleurogram shape, texture crudeness, ornamentation wall, and surface ornamentation. A total of 12 species were collected. The study reveals that the seed types alters from psilate to rugose, pleurogram shape from lunar to U shape, hilum shape from elliptical to depressed, hilum position from terminal to subterminal, fracture line pattern from reticulate irregular ridges to psilate with regular ridges, texture crudeness from fine to coarse, surface ornamentation from reticulate to psilate, and ornamentation wall also varies from thin to thick.

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The quality assurance and authentication of crude herbal drugs play important role in the effective therapeutic effect of herbal drug and their products. There are many reported problems in quality assurance of herbal crude drugs concerning to their correct identification. The present study was designed with the aim to document the authentication and quality assurance of the herbal crude drugs (Argyrolobium roseum and Viola stocksii) thorough light microscopy (LM) and scanning electron microscopy (SEM).

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Background: The weakest link in the whole cycle of chemical quality testing of sweet potato tubers for both food and feed purposes, where the main determinant of their nutritional value is the level of protein and its nutritional value, is the effect of nitrogen fertilization. Therefore, the aim of the study was to determine the effect of differentiated nitrogen fertilization on protein content and its amino acid composition, biological value, and the possibility of modification of these features.

Results: Changes in total nitrogen content in sweet potato tubers were accompanied by changes in amino acid composition of protein.

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Introduction: Diabetes mellitus (DM) is a primary disease of the carbohydrate metabolism that is characterised by absolute or relative insulin deficiency, or insulin resistance. Although life expectancy is low for diabetic patients, the prognosis has been improved in recent decades. Metformin is an oral antidiabetic that reduces insulin resistance and plasma glucose levels by decreasing glucose production in the liver.

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The Hypnaceae is one of the largest and diversified family among the pleurocarpous mosses which consists of nearly 60 genera and 1,000 species around the world. In Pakistan, it is represented by 15 species and 8 genera. The current research article provides the detail morphological investigation of four different species (genera) of the family Hypnaceae that is, Gollania clarescens, Hypnum revolutum, Homomallium andoi, and Taxiphyllum taxirameum in the Western Himalayas, Pakistan.

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Plant-based drugs have reached remarkable acceptability as therapeutic remedy for various diseases due to the adverse effects of contemporary medicines. This increasing popularity of herbal drugs leads to a growing herbal market for the development of plant-based drugs, nutraceuticals, pharmaceuticals and cosmeceuticals. Herbal drug adulteration is a complex problem which currently has undeniable consequences on health and nutrition.

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Objectives: This study aims to examine the effects of sorafenib on a collagen-induced arthritis model.

Materials And Methods: The study included 50 randomly selected female Wistar-albino rats (8-10-week-old, weighing between 200 g to 250 g). The rats were divided into five equal groups as control, arthritis, etanercept, sorafenib high-dose, and sorafenib low-dose groups, respectively.

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Background: A protein tyrosine phosphatase non-receptor type 22 (PTPN22) C1858T gene polymorphism has been reported to be associated with both Type 2 diabetes mellitus (T2DM) and Hashimoto's thyroiditis (HT) separately. However, no study has been conducted to explore the C1858T polymorphism in T2DM and HT coexistent cases up to now.

Aims: The study aimed to determine whether a relationship exists or not between the PTPN22 C1858T polymorphism and this coexistent patient group.

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