Publications by authors named "Ferzana Amod"

Background: The human immunodeficiency virus (HIV) causes movement disorders in persons living with HIV (PLH).

Objectives And Methods: We conducted a systematic review on the spectrum of movement disorders in PLH using standard terms for each of the phenomenologies and HIV.

Results: Movement disorders in PLH were commonly attributed to opportunistic infections (OI), dopamine receptor blockade reactions, HIV-associated dementia (HAD), presented during seroconversion, developed due to drug reactions or antiretroviral therapy (ART) itself and lastly, movement disorders occurred as a consequence of the HIV-virus.

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Parkinson's Disease remains a diagnostic challenge. Misdiagnosis during life is approximately 25%. Diseases that resemble PD clinically, such as the Parkinsonianplus disorders usually have a poorer prognosis.

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South Africa has the world's largest antiretroviral programme which has resulted in an increase in life expectancy in persons living with HIV. Parkinson's disease (PD) is an age-related neurodegenerative disorder. No data has been published in this setting with regards to the interaction between PD and people infected with HIV.

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Article Synopsis
  • Limited data exists on Parkinson's disease (PD) in South Africa, with a study analyzing hospital records from 2002-2016 identifying 414 PD patients across various ethnic groups.
  • The median age of onset was 60 years, with a male predominance and no significant differences in clinical profiles among ethnicities, although Indian and White patients exhibited more severe symptoms.
  • The findings indicate an increasing prevalence of PD, emphasizing the importance of allocating healthcare resources for neurodegenerative disorders in an aging African population.
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