Publications by authors named "Ferry de Klein"

Article Synopsis
  • Nerve damage activates the complement system, leading to the formation of the membrane attack complex (MAC), which impairs recovery in the peripheral nervous system.
  • A new monoclonal antibody, CP010, has been developed to target and inhibit the complement component C6, preventing MAC formation and enhancing recovery after nerve injury.
  • In tests with transgenic rats, CP010 showed promising results in preventing diseases like experimental autoimmune myasthenia gravis and reducing relapse in encephalomyelitis, suggesting its potential as a therapeutic treatment for neuronal conditions.
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