[Oncofertility and breast cancer at Montpellier University Hospital: Retrospective analysis of patients management since 2011].

Objective: Five to 7% of breast cancers affect women under 40 years old. The survival of these patients has been improved thanks to therapeutic advances, often to the detriment of their fertility. The objective of this study is to evaluate the activity of oncofertility and the future of young women with breast cancer managed at the Montpellier University Hospital.

[Quality of oocytes and embryos from women with polycystic ovaries syndrome: State of the art].

The frequency of polycystic ovary syndrome (PCOS) and the consequent fertility disorders cause many difficulties in the management of the assisted reproductive technics. Some studies are focused on different additional treatments, stimulation protocols or techniques that could optimize the in vitro fertilization cycles. The quality of the oocytes and embryos of these patients is also an outstanding issue.

Circulating microRNAs in follicular fluid, powerful tools to explore in vitro fertilization process.

Circulating or "extracellular" microRNAs (miRNAs) detected in biological fluids, could be used as potential diagnostic and prognostic biomarkers of several disease, such as cancer, gynecological and pregnancy disorders. However, their contributions in female infertility and in vitro fertilization (IVF) remain unknown. This study investigated the expression profiles of five circulating miRNAs (let-7b, miR-29a, miR-30a, miR-140 and miR-320a) in human follicular fluid from 91 women with normal ovarian reserve and 30 with polycystic ovary syndrome (PCOS) and their ability to predict IVF outcomes.

[Effects of artificial shrinkage prior to vitrification in a closed system: a randomized controlled trial].

Objective: To evaluate the effect of induced blastocoele shrinkage before vitrification in a closed carrier device.

Patients And Methods: Prior to vitrification, blastocyst cavity was artificially shrinked by laser pulse or not treated according to a 2:1 randomized procedure. A total of 185 warming cycles from April 2011 to March 2013 have been analyzed.

[Oncofertility program at the Montpellier university hospital 2 years after].

Objective: Female fertility preservation in the context of cancer management is crucial for patient's health care. The aim of this study was to evaluate the oncofertility practice at our university hospital of Montpellier since 2011.

Patients And Methods: The evaluation of management of young patients referred to Montpellier University Hospital from September 2011 to September 2013 for oncofertility counselling before cancer treatment.

[Circulating nucleic acids and in vitro fertilization].

During the last years, the use of circulating nucleic acids (microRNAs and cell-free DNA) as diagnostic and/or prognostic tools in cancerology was widely documented. Likewise, in obstetrics and gynecology, the development of non-invasive prenatal testing based on the assessment of these biomarkers confirmed their growing interest in this speciality. In human reproduction, several studies were interested in the microRNAs, small non-coding RNA sequences, present in the ovarian follicle and their implication in folliculogenesis.

[Does embryo morphology constitute a reliable criterion for embryo selection?].

Embryo selection based exclusively on embryo morphological criteria does not allow currently to obtain satisfactory implantation rates. So, new time-lapse systems have been proposed to improve the rates of in vitro fertilization success. However, the profit/investment ratio of time-lapse systems and the interest of embryo morphokinetics evaluation remain clearly to be established by clinical, robust, prospective, and randomized trials.

Experimental soybean meal intoxication in cattle.

Background: Cattle are commonly fed soybean meal (SBM) and accidental intoxication sometimes occurs.

Objectives: To describe the biologic and clinical features of SBM intoxication.

Animals: Four steers with ruminal cannula.

Investigation of the aetiology of udder-thigh dermatitis in French dairy cattle.

Udder-thigh dermatitis (UTD) is a common disease in dairy cattle. The aim of this study was to define UTD incidence, its risk factors and the involved pathogens. Of 74 respondents, 72 (97%) reported having had the disease.