In Vitro Biochemical Control of Taenia solium and Taenia saginata Eggs.

Purpouse: The present study evaluated in vitro the action of the plant protease papain (EC 3.4.22.

Evaluation of the adherence of municipalities and states to the Ministry of Health's microplanning for high-quality vaccination activities and the increase in vaccination coverage in Brazil.

Background: Immunization is a significant public health achievement for the whole world, although the population's adherence to vaccination efforts remains a concern. To address this, Brazil's Ministry of Health introduced the concept of operational microplanning (OM) for high-quality vaccination activities (HQVA) in 2023 to ensure excellence in routine service and campaigns. OM is defined by structured interventions using assertive techniques to enhance the likelihood of covering a broader population previously unprotected from vaccine-preventable diseases.

Silver Nanoparticles from : Evaluation of Potential Ovicidal Activity on Eggs.

The filtrate of the nematophagous fungus produces silver nanoparticles (AgNPs) with nematicidal potential. However, there are currently no reports of its activity against eggs. The aim of this study was to investigate the potential ovicidal activity of AgNPs- on eggs.

Microplanning workshops for high-quality vaccination in Brazil: an experience report, 2023.

Objective: To report the experience of workshops designed for action plans in microplanning vaccination in Brazilian states and municipalities.

Methods: This was a report on microplanning workshops aimed at mapping the local population, target population and identifying appropriate and effective vaccination actions. Vaccination actions were planned according to the reality of the municipalities using the microplanning method for high-quality vaccination activities.

Mortality patterns in candidemia: Insights from a multispecies analysis using a global research network.

Understanding the impact of different Candida species on patient outcomes is crucial for effective management and treatment strategies. This study aims to comprehensively analyze the association between Candida species and mortality in documented candidemia. We queried TriNetX, a global research network database, to identify patients diagnosed with candidemia through polymerase chain reaction from 2020 to 2023.

Polymethoxyflavones from Gardenia oudiepe and semi-synthetic derivatives reduce nociception in mice: Evidence for the involvement of the MAPK pathway.

This study explores the potential of polymethoxyflavones (PMFs) and polyacetylated flavones (PAFs) as novel analgesic and anti-inflammatory agents. Eight derivatives, isolated from Gardenia oudiepe bud exudate or semi-synthesized from commercial kaempferol, underwent evaluations in various in vivo, in vitro, and in silico models. Acetic acid-, formalin-induced pain, and hot-plate tests were conducted in mice (n = 6).

Protective role of TRPV1 nociceptive neurons communication to macrophages against infection in mice.

Chagas' disease is a life-threatening condition caused by . Patients with chronic disease may develop gastrointestinal, neurological, or associated neuro-digestive dysfunctions. CNS invasion by can occur in the acute phase, and its presence in the brain and cerebrospinal fluid was reported.

Fibre post removal using ultrasonic tips: A comparative in vitro study using different protocols.

This study evaluated the glass fibre post (GFP) removal using three different protocols with ultrasonic tips. Thirty-six extracted single-rooted teeth were endodontically treated and cemented with a 10-mm GFP. Three protocols were used for GFP removal: 20 s activated with cooling, 20 s activated without cooling and 40 s activated without cooling.

Implementing active surveillance for low-risk thyroid carcinoma into clinical practice: collaborative recommendations for Latin America.

The incidence of thyroid cancer is increasing globally, but mortality rates have remained steady. Many patients with thyroid cancer have low-risk, nonmetastatic intrathyroidal tumors smaller than 2 cm. Active surveillance has shown benefits in these patients, but the adoption of this approach remains below standard in Latin America.

Active surveillance versus immediate surgery in the management of low-risk papillary thyroid microcarcinoma: comparison of long-term costs in Brazil.

Objective: To compare the long-term medical costs of active surveillance (AS), partial thyroidectomy (PT), and total thyroidectomy (TT) in patients with low-risk papillary thyroid microcarcinoma (PTMC) receiving care covered by the Brazilian Public Health System.

Materials And Methods: After reviewing AS cohorts and our own data, we created a model of AS, PT, and TT flow care for low-risk PTMC over 10, 20, and 30 years. The medical costs included those associated with diagnosis, surgery, and follow-up.

Microbiological Quality of Coconut Water Sold in the Grande Vitória Region, Brazil, and Phenogenotypic Antimicrobial Resistance of Associated Enterobacteria.

This study aimed to evaluate the microbiological quality of coconut water sold from street carts equipped with cooling coils or refrigerated at bakeries in the Grande Vitória Region, Brazil. Additionally, it assessed the phenotypic and genotypic antimicrobial resistance profiles of isolated enterobacteria. The results indicated that coconut water sold at street carts had lower microbiological quality compared to refrigerated samples, as evidenced by significantly higher counts of mesophilic microorganisms.

Impact of a simple informative leaflet on Brazilian doctors' attitudes towards active surveillance of thyroid microcarcinomas.

Introduction: Active surveillance (AS) is increasingly recognized as an appropriate strategy for selected patients with papillary thyroid microcarcinomas (PTMC). However, some factors, including physician-related ones, hinder its widespread adoption.

Methods: To explore the prevailing barriers and the impact of information on attitudes towards AS implementation, we developed a questionnaire that was completed before and after reading a simple information leaflet by 317 doctors working in different work environments.

The diagnostic and prognostic role of miR-146b-5p in differentiated thyroid carcinomas.

Introduction: Samples classified as indeterminate correspond to 10-20% of cytologies obtained by fine needle biopsy of thyroid nodules, preventing an adequate distinction between benign and malignant lesions and leading to diagnostic thyroidectomies that often prove unnecessary, as most cases are benign. Furthermore, although the vast majority of patients with differentiated thyroid cancer (DTC) have such a good prognosis that active surveillance is permitted as an initial therapeutic option, relapses are not rare, and a non-negligible number of patients experience poor outcomes. MicroRNAs (miR) emerge as potential biomarkers capable of helping to define more precise management of patients in all these situations.

Three New Polyprenylated Benzophenone Derivatives Isolated from Clusia burle-marxii.

Three new polyprenylated benzophenone derivatives named burlemarxiones G-I (1-3) were isolated from C. burle-marxii trunks (compound 1) and leaves (compounds 2 and 3), along with the known compound burlemarxione F. Burlemarxione G (1) was isolated after methylation with diazomethane and it is the keto-enol tautomeric pair of burlemarxione F.

Genome-wide identification of the GDSL-type esterase/lipase protein (GELP) gene family in Ricinus communis and its transcriptional regulation during germination and seedling establishment under different abiotic stresses.

GDSL-type esterase/lipase protein (GELP) genes are crucial in the specialized lipid metabolism, in the responses to abiotic stresses, and in the regulation of plant homeostasis. R. communis is an important oilseed crop species that can sustain growth and productivity when exposed to harsh environmental conditions.

First trials exploring the potential of phytoseiid mites in managing lychee erinose mite, Aceria litchii (Keifer) (Acari: Eriophyidae), infestations on lychee plants.

Phytoseiid mites have been frequently found in association with the lychee erinose mite, Aceria litchii, on lychee plants in Brazil, suggesting that they are promising candidates as biological control agents against this pest. Here, we investigated whether phytoseiids would suppress A. litchii infestation, i.

Antimicrobial Potential of Chitosan Films Incorporated with Alcoholic Extract from Mimosa tenuiflora Leaves.

Antimicrobial films were prepared with chitosan containing the methanolic extract of M. tenuiflora leaves (FECT20 %, FECT30 %, and FECT40 %), and their antimicrobial activities were evaluated by agar diffusion. The films were characterized by IR spectroscopy, scanning electron microscopy (SEM) and TG/DTG curves.