[The value of acetylcholinesterase inhibitor therapy in the serious phases of Alzheimer's disease].

Introduction: The effectiveness of these drugs in the serious stages of the disease has still to be determined. No studies have been published which evaluate the possible influence of pharmacological therapy in patients in the serious stages of Alzheimer type dementia.

Aims: The aim of this study is to compare the progress of deterioration between patients in serious stages of the disease submitted to treatment with anticholinesterase drugs (ACD) and those who, for some reason, are not currently taking them.