Role of levetiracetam in refractory seizures due to a rare progressive myoclonic epilepsy: Lafora body disease.

Lafora disease is one of the rare, most fatal progressive myoclonic epilepsies reported. We present a case of a teenager with intractable seizures and progressive mental decline, diagnosed as Lafora body disease on axillary skin biopsy. He was admitted with status epilepticus with refractory myoclonic and generalised tonic clonic seizures.

Posterior reversible leukoencephalopathy.

Posterior Leukoencephalopathy is a rare, though reversible complication of eclampsia. We report two cases, in which patients with eclampsia presented with seizures, visual disturbances and focal neurological signs with high intensity areas predominantly in parieto-occipital white matter on cranial MRI, where successful control of blood pressures led to complete resolution of neurological deficits as well as radiological abnormalities. It is an infrequently recognized neurological disorder, not known to many physicians, which has almost complete recovery with early diagnosis and treatment.