[The prothrombotic state in early stages of chronic chagas' disease].

Objective: This study was designed to explore the presence of a prothrombotic state in the early stages of chronic Chagas' disease by evaluating serum markers of thrombosis and fibrinolysis.

Patients And Method: Forty-two patients with chronic Chagas' disease (12 men and 30 women, 32.5 6.

Facilitated thrombolysis: dethrombosis?

Intracoronary thrombus formation results from the combined effects of platelet aggregation and fibrin formation. Fibrinogen plays a significant role in each of these components. Dethrombosis is a therapeutic approach that allows dissolution of a recent thrombus while avoiding the potent fibrinolytic therapies.