Quality of life in adults with sickle cell disease: an integrative review of the literature.

Objective: To identify the available evidence in the literature on health-related quality of life in adults with sickle cell disease.

Method: integrative review of MEDLINE, CUMED, LILACS and SciELO databases, from articles developed in this area, published between 2005 and 2015, in English, Portuguese or Spanish.

Results: 22 articles were included, six scales were used to evaluate health-related quality of life scores: three generic and three specific.