Publications by authors named "Fernando Pimentel Dos Santos"
Article Synopsis
- Psoriatic disease (PsD), which includes psoriasis and psoriatic arthritis, negatively impacts patients' quality of life and requires a multidisciplinary approach involving dermatology and rheumatology for effective management and treatment.
- In Portugal, five hospitals have established specialized clinics for assessing PsD, each with unique operational models while agreeing on core assessment criteria that include all disease manifestations and quality of life.
- The main goal of these clinics is to achieve remission or minimal disease activity, though they face challenges such as financial limitations, time management, and resource constraints in implementing effective integrated care.
Objectives: To evaluate construct validity, interpretability, reliability and responsiveness as well as determination of cut-off points for good and poor health within the original English version and the 18 translations of the disease-specific Assessment of Spondyloarthritis international Society Health Index (ASAS HI) in 23 countries worldwide in patients with spondyloarthritis (SpA).
Methods: A representative sample of patients with SpA fulfilling the ASAS classification criteria for axial (axSpA) or peripheral SpA was used. The construct validity of the ASAS HI was tested using Spearman correlation with several standard health outcomes for axSpA.
Biosimilars are new and more affordable similar versions of previously approved reference biological drugs. Following the approval of the first monoclonal antibody biosimilar in 2013, the Portuguese Society of Rheumatology issued a position paper on the use of biosimilars in rheumatic conditions covering efficacy, safety, extrapolation, interchangeability, substitution and pharmacovigilance. However, as this is a rapidly evolving field, it was felt that the knowledge and evidence gathered since then justified an update of these statements.
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