Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans.

While the effect of exercise on white adipose tissue browning and metabolic improvement in rodents is clear, there are few studies in humans with inconclusive results. Thus, the aim of the study was to assess whether an exercise intervention promotes subcutaneous adipose tissue browning in humans, and whether this response is associated with metabolic improvement in three groups of individuals defined by body mass index (BMI) (kg/m). Sedentary adult subjects with different BMI were enrolled in a 12-week bicycle-training program (3 times per week, intensity 70-80% HRmax).

Repair of total anomalous pulmonary venous return: results after 47 years.

We present herein the case of a 48-year-old patient who had undergone repair of total anomalous pulmonary venous return at the age of 14 months, in March 1960, at Texas Children's Hospital. When this patient voluntarily underwent re-examination in 2007, echocardiography revealed the late results of surgery that had been performed 47 years earlier: normal pulmonary venous velocity, patent pulmonary venous return, and no substantial electrocardiographic abnormalities. This patient is perhaps the oldest known survivor of surgical repair of total anomalous pulmonary venous return.