Objective: To evaluate the relationship between the occurrence of pancreatic fistula after pancreatojejunal anastomosis in patients undergoing pancreaticoduodenectomy for periampullary malignancy and the histological fibrosis and inflammation found in pancreatic tissue and the caliber of the main pancreatic duct.
Methods: We conducted a retrospective study with patients that were treated with surgical resection. The rate of pancreatic fistulae was recorded.