Publications by authors named "Fernando F Barcelos"
The design, synthesis, docking studies and evaluation of the antifungal and cytotoxic properties of eugenol (EUG) containing 1,2,3-triazole derivatives are reported. Most of the derivatives have not been reported. The EUG derivatives were synthesized, molecular docked and tested for their antifungal activity.
View Article and Find Full Text PDFFungal infections have emerged worldwide, and azole antifungals are widely used to control these infections. However, the emergence of antifungal resistance has been compromising the effectiveness of these drugs. Therefore, the objective of this study was to evaluate the antifungal and cytotoxic activities of the nine new 1,2,3 triazole compounds derived from thymol that were synthesized through Click chemistry.
View Article and Find Full Text PDFArticle Synopsis
- The use of synthetic herbicides in agriculture faces challenges due to health and environmental concerns, as well as increasing weed resistance.
- Researchers synthesized glycerol-fluorinated triazole derivatives to evaluate their effectiveness in weed control, focusing on their potential low toxicity and efficiency.
- Testing on Lactuca sativa showed varying levels of phytotoxic and cytogenotoxic effects, suggesting these compounds could serve as a new approach for weed management.