Publications by authors named "Fernando Dominguez Rodriguez"
Introduction And Objectives: Vaccines against SARS-CoV-2 have been a major scientific and medical achievement in the control of the COVID-19 pandemic. However, very infrequent cases of inflammatory heart disease have been described as adverse events, leading to uncertainty in the scientific community and in the general population.
Methods: The Vaccine-Carditis Registry has included all cases of myocarditis and pericarditis diagnosed within 30 days after COVID-19 vaccination since August 1, 2021 in 29 centers throughout the Spanish territory.
Article Synopsis
- The study investigates the impact of genetic variations (SNPs) in the ACE2 and related genes on the severity of COVID-19 among patients, revealing some SNPs provide protective effects while others increase risk of severe outcomes.
- A total of 318 COVID-19 patients were categorized based on their symptoms, with analyses highlighting the relationship between specific SNPs and disease severity, alongside traditional risk factors like age and comorbidities.
- Key findings show that certain ACE2 SNPs can significantly influence disease progression, with two SNPs linked to protective effects and two others associated with higher risk for hospitalization and severe illness.
Background: Urinary sodium excretion predicts long-term adverse events after discharge in patients with acute heart failure (AHF). The role of natriuresis as an early marker of poor diuretic response during an AHF episode has been scarcely investigated. We sought to evaluate whether early natriuresis or its change during heart failure hospitalization is associated with the development of in-hospital diuretic resistance (DR).
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