Does waterpipe smoke induce genotoxicity (DNA damage) in mammalian cells ? A systematic review.

The waterpipe works by placing tobacco in a bowl with holes at the bottom, which is connected to a tube leading to a water-filled container. Upon heating the tobacco product with hot charcoal placed atop it, the emanating smoke is inhaled by the user a hose linked to the water receptacle. The aim of this literature review is to evaluate whether the use of waterpipes can indeed induce genotoxicity in mammalian cells .

Risk factors for the population's mental health amidst the COVID-19 pandemic.

Objective: To identify risk factors for mental health in the population in times of COVID-19 through the analysis of levels of socio-cognitive mindfulness and perception of stress in individuals.

Method: This is a cross-sectional observational study with a quantitative approach, carried out through online data collection using the Perceived Stress Scale and the Langer Mindfulness Scale in a sample of 955 individuals from different regions of Brazil.

Results: Women, younger people and individuals with low socioeconomic conditions had higher levels of perceived stress; on the other hand, older men and individuals with high socioeconomic status had higher levels of mindfulness.

Laser-Modified Ti Surface Improves Paracrine Osteogenesis by Modulating the Expression of DKK1 in Osteoblasts.

Titanium surface modifications are widely used to modulate cellular behavior by recognition of topographical cues. However, how those modifications affect the expression of mediators that will influence neighboring cells is still elusive. This study aimed to evaluate the effects of conditioned media from osteoblasts cultured on laser-modified titanium surfaces on the differentiation of bone marrow cells in a paracrine manner and to analyze the expression of Wnt pathway inhibitors.

Pam2CSK4 (TLR2 agonist) induces periodontal destruction in mice.

Lipoproteins are important bacterial immunostimulating molecules capable of inducing receptor activator of nuclear factor-κB (RANKL) and osteoclast formation in vitro and in vivo . Although these molecules are present in periodontopathogenic bacteria, their role in periodontitis is not known. In this study, we used Pam2CSK4 (PAM2), a synthetic molecule that mimics bacterial lipoprotein, to investigate the effects of lipoproteins on periodontitis in mice.

Antimicrobial effects of terpinen-4-ol against oral pathogens and its capacity for the modulation of gene expression.

This study evaluated the antibacterial activity of terpinen-4-ol against and and its influence on () and () gene expression. As measured by XTT assay, the concentrations of terpinen-4-ol that effectively inhibited the biofilm were 0.24% and 0.

Polymerization Shrinkage of Bulk Fill Composites and its Correlation with Bond Strength.

The present study aimed to evaluates polymerization shrinkage (PS) using microcomputed tomography (μCT) and microtensile bond strength (μTBS) in bulk fill composites (BFC) and conventional class I restorations as well as the correlation between these factors. Class I cavities (4 x 5 x 4 mm), factor-C = 4.2, were created in third molars that were free of caries, which were randomly divided in 4 groups (n = 6): XTI (Filtek Supreme XTE: incremental technique); XTB (Filtek Supreme XTE: single fill technique); TBF (Tetric Bulk Fill); and SF (SonicFill).

Systemic effect of mineral aggregate-based cements: histopathological analysis in rats.

Objective: Several studies reported the local tissue reaction caused by mineral aggregate-based cements. However, few studies have investigated the systemic effects promoted by these cements on liver and kidney when directly applied to connective tissue. The purpose of this in vivo study was to investigate the systemic effect of mineral aggregate-based cements on the livers and kidneys of rats.

Incontinentia pigmenti presenting as hypodontia in a 3-year-old girl: a case report.

Introduction: Incontinentia pigmenti or Bloch-Sulzberger syndrome is a rare X-linked dominant disease that mainly affects the skin, eyes, hair, central nervous system and teeth. The disease is predominant among women. Although dermatologic manifestations are among the most important aspects for the diagnosis of the syndrome, they are less damaging to the patient and do not require treatment.