Publications by authors named "Fernandez-Vela J"
Article Synopsis
- - A study evaluated the effectiveness and safety of dupilumab for treating bullous pemphigoid in elderly patients, with a focus on those who typically have other health issues that make standard treatments unsuitable.
- - The results showed that 53.4% of patients achieved complete remission within 4 weeks and 95.7% by week 52, with a significant reduction in itchiness and a dramatic decrease in the need for corticosteroids.
- - The treatment was found to be safe, with most adverse events being mild, and factors like shorter disease duration and exclusive skin involvement were linked to better treatment responses.
Article Synopsis
- Localized bullous pemphigoid (LBP) is a rare skin condition affecting specific body areas, often triggered by local factors in patients with pre-existing antibodies against the basement membrane.
- A study of 7 patients showed various local triggers such as surgery and burns, and introduced diagnostic criteria based on the findings and existing guidelines.
- Follow-up revealed that 3 patients progressed to generalized bullous pemphigoid, with many LBP cases linked to prior injuries, particularly affecting older women and frequently involving the lower limbs.
Background: Reconstruction of surgical defects located close to eyelid edges, nostrils, or the mouth is challenging, as tension generated by direct closure or skin flaps in these sensitive regions tends to cause distortion. New repair techniques that prevent retraction may significantly improve outcomes.
Patients And Methods: Retrospective study of the use of 2 novel flap designs-the nautilus flap and the bullfighter crutch flap-to repair surgical defects in the peripalpebral, perivestibular, nasal, and perioral areas.