Immunogenicity, reactogenicity and safety of an inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine: a phase III, randomized trial in adults aged ≥18 years.

Background: Two antigenically distinct influenza B lineages have co-circulated since the 1980s, yet inactivated trivalent influenza vaccines (TIVs) include strains of influenza A/H1N1, A/H3N2, and only one influenza B from either the Victoria or Yamagata lineage. This means that exposure to B-lineage viruses mismatched to the TIV is frequent, reducing vaccine protection. Formulations including both influenza B lineages could improve protection against circulating influenza B viruses.

[Assessment of the impact of the use single-dose medications in 2 primary care centres].

Objective: To evaluate the economical impact of using medications packaged in a single dose non-reusable container (Onedose(®)), compared to prescribing preparations in the usual multidose containers.

Design: We performed a cost-minimization analysis from a prescribing center's perspective. The observational study design is retrospective and analyzes 23 products in prescriptions made between January and April 2012.

[Adjusted clinical groups use at a Spanish primary care center: a retrospective, population-based study].

Objectives: To evaluate the results of implementing a classification system based on adjusted clinical groups (ACG) at a primary health care (PHC) in a Spanish population.

Methods: A retrospective, cross-sectional study based on the computerized medical records of outpatients seen in 2007 by the La Roca clinic, administered by a health services management company in La Roca del Vallès, Barcelona, Spain. The ACGs were formed according to the International Classification of Diseases, 9th Revision, Clinical Modification.

[Imported hookworm infection in African immigrants in Spain: study of 285 patients].

Background And Objective: Hookworm infection is a worldwide intestinal parasitic disease affecting more than one billion people. It represents an important public health problem in rural areas of developing countries. In our environment, it is generally considered an imported disease due to the immigration process.

[Imported diseases in African immigrants in Spain: study of 1,321 patients].

Background: Immigrants can carry diseases characteristic from their countries of origin. These are known as imported diseases (ID) and can be classified into tropical diseases (TD) or cosmopolitan diseases (CD). The aim of this study was to analyse the ID in African immigrants and evaluate their repercussion in the Spanish Public Health.

[Imported paludism: an emerging illness].

Background: We aimed at knowing the epidemiological and clinical characteristics of imported malaria in Maresme county (Barcelona), Spain.

Patients And Method: A descriptive and retrospective study of patients diagnosed with imported malaria at the Hospital de Mataró (HM) (1982-2000).

Results: 64 cases of malaria were diagnosed, which supposed a significant increase in its incidence over the last decade.

Comparative, clinico-epidemiologic study of Schistosoma mansoni infections in travellers and immigrants in Spain.

The study presented here aimed to contrast the marked clinical differences in the presentation of Schistosoma mansoni-induced infection between immigrants and travellers entering Spain from endemic regions, and to elucidate the therapeutic implications of these infections. A total of 200 African immigrants and 80 travellers with schistosomiasis were included in the study. Among the immigrants, 25 patients were diagnosed with Schistosoma mansoni infection; 15 presented with nonspecific symptoms, and 10 were asymptomatic.

[Demographic characterization, consultation reasons and prevalent morbidity in the African immigrating community of the Maresme district].

Background: To know the demographic condition, main symptoms and diagnosis in adult African immigrants from a reference Hospital.

Patients And Method: A prospective protocol between 1984-1994.

Results: 1,321 immigrants were considered.