Publications by authors named "Fernandez Suarez Marcos"
Limbic encephalitis (LE) associated with positive potassium channel complex antibodies often manifests with faciobrachial dystonic seizures (FBDS). We retrospectively analyze two cases, admitted to our video-EEG unit between 2006 and 2014. Both patients were males, aged 66 and 76 years respectively, presenting with brief, but very frequent uni/bilateral dystonic brachial movements, hand posturing and ipsilateral facial grimacing.
View Article and Find Full Text PDFBackground: The purpose of this study was to investigate the relationship between cognitive reserve and concentration of Aβ1-42 in the cerebrospinal fluid (CSF) of patients with mild cognitive impairment, those with Alzheimer's disease, and in control subjects.
Methods: Thirty-three participants from the Argentina-Alzheimer's Disease Neuroimaging Initiative database completed a cognitive battery, the Cognitive Reserve Questionnaire (CRQ), and an Argentinian accentuation reading test (TAP-BA) as a measure of premorbid intelligence, and underwent lumbar puncture for CSF biomarker quantification.
Results: The CRQ significantly correlated with TAP-BA, education, and Aβ1-42.
Concordance between 11C-PIB-PET and clinical diagnosis in a memory clinic.
Am J Alzheimers Dis Other Demen
September 2015
Article Synopsis
- Positron Emission Tomography (PET) can visualize fibrillar β-amyloid, which is important for assessing Alzheimer's Disease (AD), but merely detecting amyloid plaques isn't enough for a definitive diagnosis.
- The study grouped 144 patients into high and low pre-test probability categories based on clinical diagnoses related to AD, examining the prevalence of amyloid findings in different dementia syndromes.
- Results indicated that only normal controls and Dementia of Alzheimer's Type showed consistent diagnostic results, while other conditions like MCI and Frontotemporal Dementia displayed significant discrepancies between clinical evaluations and molecular imaging outcomes.
Introduction: The Clinical Dementia Rating Scale (CDR) is a tool designed to quantify the severity of dementia symptoms and is also useful to assess disease progression, in Alzheimer's disease (AD). A new version of the scale was developed by adding two extra domains that focused on the core aspects of frontotemporal dementia symptomatology, Language and Behavior/Comportment/Personality.
Objectives: In this study, we adapted and validated the modified CDR scale in our setting and language (Rioplatense-Spanish).
Objectives: This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic.
Method: A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (p.o.