The construction and defense of nests leading up to and following spawning is widespread across freshwater fishes. Despite the known role of nesting in sexual selection and the establishment of social hierarchy, how nesting and nest guarding behavior may shape predation risk for both offspring and nest guarding individuals remains relatively underexplored for many species. Here, we documented a novel interaction between a nest guarding fish species, the pumpkinseed sunfish (), and common snapping turtles () during the pumpkinseed nesting period.
View Article and Find Full Text PDFThis study is focused on the fabrication and characterization of various dual waveguides through femtosecond (fs) laser irradiation of GeO-based glass samples. The objective of the present work is to develop diverse waveguide configurations, namely straight, S-bend and Y-shaped waveguides within GeO-PbO glasses embedded with silver nanoparticles, utilizing a double-guide platform, for photonic applications such as resonant rings and beam splitters. Enhanced guidance was observed with a larger radius of curvature (80 mm) among the two distinct S-bend waveguides produced.
View Article and Find Full Text PDFIntroduction: Health insurance coverage can serve as protection against catastrophic health expenditures. Section 21 (4) of the Mental Healthcare Act, 2017 (MHCA) mandates insurance coverage for mental illness to be on par with that for physical illness. Despite this, anecdotal evidence shows persons with mental health conditions are routinely denied or face difficulties in obtaining medical insurance coverage due to their mental illness.
View Article and Find Full Text PDFTracheal congenital defects are infrequent but serious findings in animals. Tracheal diverticula are congenital air-filled cystic lesions, a sub-type of paratracheal air cyst mainly found extra-thoracically in foals. We describe a case in a twelve-day old show Arabian colt with right sided unilateral cervical swelling since birth.
View Article and Find Full Text PDFToxoplasmosis is an alarming public health problem that affects more than one-third of the world's population. In our work, we investigated the antiparasitic effects of catalytically active [BpMP-I and Jararhagin (Jar)] and catalytically inactive [Jararhagin-C (Jar-C)] snake venom metalloproteinases (SVMPs) in human HeLa cells. These toxins impaired the parasite invasion and intracellular growth, and modulated IL-6, IL-8, and MIF cytokines that control the cell susceptibility and response against .
View Article and Find Full Text PDFCurr Microbiol
February 2025
Infections by Mycobacterium spp. are responsible for thousands of deaths every year worldwide. Microbial resistance, toxic effects, and adverse consequences of conventional therapies bring forth the need to search for new therapeutic agents.
View Article and Find Full Text PDFEquine piroplasmosis (EP) is a reportable disease according to the World Organization for Animal Health (WOAH), caused by Babesia caballi, Theileria equi and T. haneyi. This syndrome is prevalent in tropical and subtropical regions, including various areas in Brazilian.
View Article and Find Full Text PDFCad Saude Publica
February 2025
Research on therapeutic itineraries in child and adolescent mental health has been predominantly carried out in Child and Adolescent Psychosocial Care Centers or in regions that have these services. To expand the understanding of this field, this study analyzed the therapeutic itineraries of children and adolescents assisted by the Multiprofessional Mental Health Team service - locally known as "Mental Health" - in an inner municipality without Child and Adolescent Psychosocial Care Centers. Semistructured interviews were conducted with 12 mothers and two fathers to understand their motivations for seeking care, the places they visited, and the experiences they had in this process.
View Article and Find Full Text PDFThe aim of this study was to assess the impact of orthodontic treatment with orthodontic aligners (OAs) and fixed appliances (FAs) on oral health-related quality of life (OHRQoL). This parallel randomized clinical trial included 40 male and female patients aged 13 to 35 years diagnosed with Angle's Class I malocclusion. Participants were assigned to two groups: OA (n = 20) and FA (n = 20).
View Article and Find Full Text PDFBackground: Low QRS complex voltage is an important predictor of death in Chagas disease. However, the parameters applied to the low-voltage classification were described by the Minnesota Code and not specifically for Chagas disease. This study aimed to analyze low QRS voltage by determining the ADOC index and averages in the frontal and horizontal electrocardiographic planes, establishing possible clinical implications.
View Article and Find Full Text PDFWine industry has faced pressure to innovate its products. Saccharomyces cerevisiae has been the traditional yeast for producing alcoholic beverages, but interest has shifted from the conventional S. cerevisiae to non-Saccharomyces yeasts for their biotechnological potential.
View Article and Find Full Text PDFRev Inst Med Trop Sao Paulo
January 2025
Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed to describe the safety of two doses of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared to immunocompetent/healthy (H) individuals. This phase 4, multicenter, open label study included solid organ transplant and hematopoietic stem cell transplant recipients, cancer patients and people with inborn errors of immunity with defects in antibody production, rheumatic, end-stage chronic kidney or liver disease, who were enrolled in the IC group.
View Article and Find Full Text PDFBackground/objectives: Cartilage injuries and osteoarthritis are prevalent public health problems, due to their disabling nature and economic impact. Mesenchymal stromal cells (MSCs) isolated from different tissues have the immunomodulatory capacity to regulate local joint environment. This translational study aims to compare cartilage restoration from MSCs from the synovial membrane (SM) and dental pulp (DP) by a tissue-engineered construct with Good Manufacturing Practices.
View Article and Find Full Text PDFPyruvate kinase M2, a central regulator of cancer cell metabolism, has garnered significant attention as a promising target for disrupting the metabolic adaptability of tumor cells. This study explores the potential of the Mannich base derived from lawsone () to interfere with PKM2 enzymatic activity both in vitro and in silico. The antiproliferative potential of was tested using MTT assay in various cell lines, including SCC-9, Hep-G2, HT-29, B16-F10, and normal human gingival fibroblast (HGF).
View Article and Find Full Text PDFNasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment.
View Article and Find Full Text PDFThis study evaluates the nutritional value of spray-dried biomass to infer its applicability for weaner piglet feeding. Twenty-four piglets were randomly allocated to four dietary treatments ( = 6) with increasing inclusion (0, 5, 10, and 15%) levels. After a 4-day adaptation period, the digestibility experiment lasted two weeks, with daily excreta collection.
View Article and Find Full Text PDFBiological variation in laboratory results refers to physiological fluctuations that occur around a homeostatic setpoint (HSP) for various laboratory measurands. Assessment of biological variation includes determining individual variation (CV), group variation (CV), and analytical variation (CV). Reference change value (RCV) is an objective tool for an evidence-based approach to interpret data by assessing the significance of consecutive results in an individual for the diagnosis, prognosis, and monitoring of disease.
View Article and Find Full Text PDFThe diagnosis of milk fever or hypocalcemia in lactating cows has a significant economic impact on the dairy industry. It is challenging to identify asymptomatic subclinical hypocalcemia (SCH) in transition dairy cows. Monitoring subclinical hypocalcemia in milk samples can expedite treatment and improve the health, productivity, and welfare of dairy cows.
View Article and Find Full Text PDFTo investigate the relationship between sociodemographic factors, musculoskeletal pain and its characteristics, and the type of primary health care received with self-reported disability. This is a cross-sectional study, interviewing individuals selected from spontaneous demand for health care in two types of care: health center and family health unit. Disability was investigated using the World Health Organization Disability Assessment Schedule (WHODAS) 2.
View Article and Find Full Text PDFEvidence suggests that paternal diet can influence offspring metabolic health intergenerationally but whether dietary animal and plant proteins differ in their impact on fathers and their offspring is not known. Our objective was to examine the effects of a paternal diet high in casein versus pea protein on fathers and their offspring. Five-week-old male rats were fed: (1) control, (2) high animal protein (AP, 36.
View Article and Find Full Text PDFThe objective of this study was to evaluate the effects of a rumen-derived direct-fed microbial (DFM) product on performance, blood biomarkers, ruminal fermentation, and bacterial abundance in dairy cows during the transition period until 100 DIM. Fifty-six Holstein cows were enrolled in a randomized complete block design from -21 to 100 DIM. Cows were blocked based on expected calving date, parity, and previous lactation milk yield for multiparous cows or genetic merit for primiparous cows.
View Article and Find Full Text PDFAssessing nutrient loading and processing is crucial for water quality management in lakes and reservoirs. Quantifying and reducing external nutrient inputs in these systems remains a significant challenge. The difficulty arises from low monitoring frequencies of the highly dynamic external inputs and the limited availability of measures to reduce diffuse source loading.
View Article and Find Full Text PDFThe roughskin dogfish Centroscymnus owstonii, a deep-sea shark, has a patchy global distribution, with most knowledge stemming from incidentally captured specimens. Using a deep-sea remote lander video system, we observed multiple C. owstonii individuals alive on the footage at 1054 m off Little Cayman, Cayman Islands, Western Atlantic Ocean, marking, to our knowledge, the first record of the species in the Greater Antilles, central Caribbean Sea, while also adding a new species locality record for the Cayman Islands.
View Article and Find Full Text PDF