Publications by authors named "Fernanda da Silveira Vargas"
This in vitro study evaluated the potential protective effect of vitamin E alpha-tocopherol (α-T) isomer against the toxicity of hydrogen peroxide (HP) applied on dental pulp cells. Odontoblast-like MDPC-23 cells were seeded on 96-well plates for 72 h, treated with different concentrations of α-T (1, 3, 5, and 10 mM) for different times (1, 4, 8, and 24 h) and then exposed or not to a 0.018% HP solution for 30 min.
View Article and Find Full Text PDFThe aim of this study was to evaluate the protective effects of different concentrations of vitamin E alpha-tocopherol (α-T) isomer against the toxicity of hydrogen peroxide (H2O2) on dental pulp cells. The cells (MDPC-23) were seeded in 96-well plates for 72 hours, followed by treatment with 1, 3, 5, or 10 mM α-T for 60 minutes. They were then exposed or not to H2O2 for 30 minutes.
View Article and Find Full Text PDFObjectives: This study aimed to evaluate and correlate the efficacy and cytotoxicity of a 35 % hydrogen peroxide (HP) bleaching gel after different application times on dental enamel.
Materials And Methods: Enamel/dentin disks in artificial pulp chambers were placed in wells containing culture medium. The following groups were formed: G1, control (no bleaching); G2 and G3, three or one 15-min bleaching applications, respectively; and G4 and G5, three or one 5-min bleaching applications, respectively.
This in vitro study evaluated different concentrations of chlorhexidine (CHX) solution on the disinfection of dentures colonised with a reference (ATCC 90028) and azole-resistant (R1, R2 e R3) strains of Candida albicans. Sterile dentures were individually inoculated with one of the strains and incubated at 37 °C for 24 h. Then, each denture was immersed in sterile saline (control) or CHX (2%, 1% or 0.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess the antibacterial effects of various chlorhexidine (CHX) concentrations against the bacteria Streptococcus mutans using two different testing methods: direct application (agar-diffusion) and indirect application (transdentinal diffusion with human dentin discs).
- The researchers prepared Petri dishes with S. mutans and tested different CHX concentrations (0.12%, 0.2%, 1%, 2%), phosphoric acid, and control groups, measuring the zones of bacterial growth inhibition after incubation.
- Results showed that higher CHX concentrations had greater antibacterial activity, with the most significant inhibition observed using 2% CHX on thinner dentin discs, indicating the effectiveness of CHX against S.