Publications by authors named "Fernanda R Paolillo"

Background And Purpose: Work-related musculoskeletal disorders (WMSDs) are an array of conditions affecting the human locomotor system, such as muscles, tendons, nerves, bones, and joints. It is related to physiological, kinesiological and biomechanical changes which result in pain, paresthesia, inflammation, weakness, tiredness, heaviness in limbs, fatigue, reduced range of motion and/or compression of peripheral nerves. The aim of this study was to investigate the therapeutic effects of positive (massage gum) or negative pressure (vacuum therapy) combined with laser on the health of workers with back pain, investigating pain intensity, shoulder mobility, spinal flexibility, life quality, and well-being.

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Post-stroke sequelae includes loss functions, such as cognitive and sensory-motor which lead to emotional and social problems, reducing quality of life and well-being. The main aim of our study was to investigate the effects of transcranial laser photobiomodulation together with neuromuscular electrical stimulation (NMES) in post-stroke patients. We performed a clinical trial and an ex vivo study.

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Photobiomodulation-PBM and Photodynamic Therapy-PDT have been used to induce healing. However, the effects of these therapies on skin-lesions induced by electrocautery are unknown, aiming at more favorable clinical and esthetic results. Electrocauterization was done in 78-female Wistar-rats using a system that includes an electrocautery and red-LED.

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Nowadays, the mesentery as a new organ was discovered. Mesenteric events may play an important role in the pathophysiology of several diseases. The aim of our study was investigate the synergic effects of ultrasound (US) and laser therapies on mesentery in obese-hyperglycemic rats.

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Background And Purpose: Overuse injuries and painful symptoms in athletes and dancers (especially classical ballerinas) may lead to reduced functional performance. However, laser application may reduce pain and increase physical conditioning. The aim of the current study was to evaluate the immediate and long-term effects of infrared laser on classical ballerinas' feet.

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Healing wounds represent a major public health problem, mainly when it is infected. Besides that, the antibiotics misuse and overuse favor the development of bacterial resistance. This study evaluated the effects of antimicrobial photodynamic therapy (aPDT) combined with artificial skin on disinfection of infected skin wound in rats.

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Article Synopsis
  • The study focused on the oral health-related quality of life (OHRQoL) of patients with temporomandibular disorders (TMDs) using a combined treatment of ultrasound (US) and photobiomodulation therapy (PBMT).
  • Thirteen patients received treatment on both sides of their face, targeting specific muscles and the temporomandibular joint over eight sessions, with OHRQoL assessed before, after, and one month post-treatment.
  • Results showed significant improvement in OHRQoL immediately after treatment, particularly in psychological discomfort and physical pain, with benefits remaining evident at the one-month follow-up.
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[Purpose] This study aims to evaluate the synergistic effects of laser therapy and vacuum therapy in the rehabilitation of some disorders of the osteomuscular articular system (shoulder bursitis, low back pain, hip dysfunction after long-term impact of femoral endoprosthesis). [Participants and Methods] Three case reports were described. A vacuum laser system was used, which is a device that contains 1 handpiece with 3 red lasers (660 nm) and 3 infrared lasers (808 nm).

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The aim of this research is to study skin autofluorescence and the associations between skin glycated proteins and clinical characteristics of healthy and unhealthy subjects for noninvasive screening of diabetes and cardiovascular disease (CVD) risks. Accumulated advanced glycation endproducts (AGEs) promote increased oxidative stress and inflammation, as well as cross-linking of proteins leading to tissue damage and several diseases, including diabetes. One hundred and four subjects with or without diabetes and stroke aged 20-80 years and with Fitzpatrick skin type (I to IV) participated in this study.

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Diabetes is a complex metabolic disease and has chronic complications. It has been considered a serious public health problem. The aim of the current study was to evaluate skin glycated proteins through fluorescence and Raman techniques.

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This study evaluated the synergistic effects of ultrasound (US) and low-level laser therapy (LLLT) with or without therapeutic exercises (TE) in women with knee osteoarthritis. Forty-two Caucasian women with knee osteoarthritis were allocated into three groups: (1) the placebo group who did not perform TE, but the prototype without emitting light or ultrasonic waves was applied, (2) the US + LLLT group in which only the prototype was applied and (3) the TE + US + LLLT group that performed TE before the prototype was applied. However, 35 women completed the full clinical trial.

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There are few published data on the relationship between loss of bone mass due to osteoporosis and poor tooth quality. This study analyzed the effects of osteoporosis on incisor teeth and femoral bones using optical techniques in rats. Twenty female Wistar rats aged 6 months (n = 20) were randomized into two groups: control group, non-ovariectomized rats (n = 10); ovariectomy group, ovariectomized rats to induce osteoporosis (n = 10).

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A cluster of metabolic abnormalities are markedly higher among postmenopausal women. The present study evaluated the effects of infrared light emitting diode (LED) during treadmill training on multiple metabolic markers, body fat, dietary habits and quality of life in postmenopausal women. Forty-five postmenopausal women aged 50-60 years were randomly assigned to one of three groups, and of these, 30 women successfully completed the full study.

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Article Synopsis
  • This study examined how demineralization affects teeth and bones in rats using two advanced techniques: fluorescence spectroscopy and micro energy-dispersive X-ray fluorescence spectrometry (μ-EDXRF).
  • The research involved both in vitro and in vivo experiments, including decalcifying the teeth of Wistar rats and comparing control and ovariectomized groups to induce osteoporosis effects.
  • Results showed that while no significant differences were observed with a 408nm laser, using a 532nm laser revealed important changes in fluorescence spectra, indicating a loss of calcium and phosphorus in the ovariectomized rats, highlighting significant implications for tissue quality assessment.
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Article Synopsis
  • The study aimed to evaluate the effectiveness of antimicrobial photodynamic therapy (aPDT) using curcumin combined with sodium dodecyl sulfate (SDS) for reducing oral bacteria in patients with orthodontic appliances.
  • A total of 24 orthodontic patients were divided into four groups to compare the effects of blue light treatment alone, aPDT with curcumin, aPDT with curcumin plus SDS, and a traditional antibacterial rinse (chlorhexidine).
  • Results showed that both aPDT methods (with and without SDS) and chlorhexidine significantly reduced bacterial colonies, indicating that aPDT, particularly with SDS, may be an effective method for improving oral health in orthodontic patients.*
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Objective: The aim of this study was to analyze the effects of low-level laser therapy (LLLT) when associated with treadmill training on the recovery of skeletal muscle, during two periods of rest after muscle injury in rats.

Background Data: Because of photostimulation, LLLT has been presented as an alternative for accelerating the tissue healing process.

Materials And Methods: Forty rats were divided into two groups (A and B) containing four subgroups each: GC (Control Group)-cryolesion untreated; EG (Exercise Group)-cryolesion treated with physical exercise; LG (Laser Group)-cryolesion treated with laser; ELG (Exercise and Laser Group)-cryolesion treated with laser and physical exercise.

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Background And Objective: Phototherapy plus dynamic exercise can enhance physical performance and improve health. The aim of our study was to evaluate the effect of low-level laser therapy (LLLT) associated with high intensity resistance training (HIT) on cardiac autonomic and muscle metabolic responses in rats.

Study Design/materials And Methods: Forty Wistar rats were randomized into 4 groups: sedentary control (CG), HIT, LLLT and HIT + LLLT.

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Objective: The purpose of this study was to evaluate the effects of the antimicrobial photodynamic therapy (a-PDT) with blue light and curcumin on oral disinfection during the 2 h after treatment.

Background Data: a-PDT is a technique that can potentially affect the viability of bacterial cells, with selective action targeting only areas with photosensitizer accumulation.

Materials And Methods: A randomized controlled trial was undertaken.

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Patients with pain avoid movements, leading to a gradual impairment of their physical condition and functionality. In this context, the use of ultrasound (US) and low-level laser therapy (LLLT) show promising results for nonpharmacological and noninvasive treatment. The aim of this study was evaluated the synergistic effects of the US and the LLLT (new prototype) with or without therapeutic exercises (TE) on pain and grip strength in women with hand osteoarthritis.

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Article Synopsis
  • Low-level laser therapy (LLLT) is commonly used for pain relief, particularly in conditions like temporomandibular disorders (TMD), but the effects of LED therapy have not been studied before.
  • This research tested the impact of red and infrared LED treatments on tissue temperature and pain relief in TMD patients, involving thirty individuals who underwent eight sessions of therapy over four weeks.
  • Results showed an increase in tissue temperature and significant reductions in pain, as well as improved jaw function, indicating that LED therapy is a promising alternative to traditional LLLT for TMD management.
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Objective: The aim of our study was to evaluate the cutaneous temperature during an exercise on a treadmill with or without infrared light-emitting diode (LED) irradiation in postmenopausal women.

Background Data: Thermography is an imaging technique in which radiation emitted by a body in the middle and far infrared spectrum is detected and associated with the temperature of the body's surface.

Materials And Methods: Eighteen postmenopausal women were randomly divided into two groups: (1) the LED group, which performed the exercises on a treadmill associated with phototherapy (n=9) and; (2) the exercise group, which performed the exercises on a treadmill without additional phototherapy (n=9).

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The aim of this study was to histologically and biochemically analyze the effects of light-emitting diode therapy (LEDT) associated with resistance training to prevent sarcopenia in ovariectomized rats. Forty female Wistar rats (12 months old, 295-330 g) were bilaterally ovariectomized and divided into four groups (n = 10 per group): control-sedentary (C), resistance training (T), LEDT-sedentary (L), and LEDT plus resistance training (LT). Trained rats performed a 12-week water-jumping program (3 days per week) carrying a load equivalent to 50-80% of their body mass strapped to their back.

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Obesity and associated dyslipidemia is the fastest growing health problem throughout the world. The combination of exercise and low-level laser therapy (LLLT) could be a new approach to the treatment of obesity and associated disease. In this work, the effects of LLLT associated with exercises on the lipid metabolism in regular and high-fat diet rats were verified.

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Reduced aerobic fitness is associated with an increased risk of cardiovascular diseases among the older population. The aim of this study was to investigate the effects of LED irradiation (850 nm) applied during treadmill training on the maximal exercise tolerance in postmenopausal women. At the beginning of the study, 45 postmenopausal women were assigned randomly to three groups, and 30 women completed the entire 6 months of the study.

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Objective: Obesity is a major public health problem leading to, among other things, reduced functional capacity. Moreover, obesity-related declines in functional capacity may be compounded by the detrimental consequences of menopause. The aim of this study was to understand the potential effects of excess body mass on measures of functional capacity in postmenopausal women.

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