Publications by authors named "Fernanda Monik Silva Martins"
The epidemiological and clinical pathological aspects of polioencephalomalacia (PEM) in five buffaloes in the Amazon biome are described. Epidemiological data were obtained during the clinical visit in which buffalos were submitted to an examination of the nervous system. The diagnosis of PEM was based on epidemiological, clinical-pathological, and histopathological findings, similar to findings in other ruminants.
View Article and Find Full Text PDFImmunization of sheep with a recombinant vaccine containing immunogenic nontoxic domains of Clostridium perfringens alpha and beta toxins.
Rafael Rodrigues Rodrigues Jaqueline Freitas Motta Marcos Roberto Alves Ferreira Clóvis Moreira Júnior Mariliana Luiza Ferreira Alves Fernanda Monik Silva Martins
Microb Pathog
September 2023
Clostridium perfringens (types A and C) can cause several diseases by secreting alpha (CPA) and beta (CPB) exotoxins in the gastrointestinal tract. Although vaccination is the main measure of immunization against C. perfringens, available vaccines have limitations in terms of productivity and safety.
View Article and Find Full Text PDFArticle Synopsis
- The Milwaukee protocol shows promise in treating rabies, but the mechanisms of drug action and immune response require further study.
- Biopterin, a drug used in the protocol, helps regulate nitric oxide levels, which is crucial in preventing blood vessel spasms.
- In experiments on animals infected with rabies, biopterin influenced inflammatory factors and helped manage the immune response, particularly concerning the blood-brain barrier and cytotoxic cell movement.