Publications by authors named "Fernanda Midori Abukawa"
is an Amazonian spider described for the first time almost a century ago. However, little is known about their venom composition. Here, we present a multiomics characterization of venom by a combination of transcriptomics, proteomics, and peptidomics approaches.
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- Trypanosoma cruzi, the parasite that causes Chagas disease, relies on reactive oxygen species (ROS) from host cells for its growth and proliferation.
- The study found that a key protein released by the parasite, TcCyp19, is crucial for raising ROS levels in host cells; without it, the parasite struggles to thrive.
- TcCyp19's presence is linked to increased ROS and parasite proliferation, indicating its vital role in the infection process and suggesting potential therapeutic targets for managing Chagas disease.