A survivor woman after three years of a cardiac tamponade.

Primary pericardial mesothelioma is an extremely rare tumor, of unclear etiology, nonspecific presentation, with a delay in diagnosis, and a poor prognosis. We present the case of a woman with pericardial mesothelioma, whose main manifestation was cardiac tamponade, currently alive three years after diagnosis and undergoing chemotherapy treatment. < Cardiac tamponade can be the first clinical manifestation of a neoplastic disease, including pericardial mesothelioma, so an adequate diagnostic approach should always be carried out in patients with this clinical picture.