Publications by authors named "Fernanda M Gazoni"
Article Synopsis
- The study aimed to explore how the proteins α-Klotho and FGF-23 relate to bone health and density in elderly individuals aged around 85.6 years.
- A total of 55 participants were analyzed through clinical and biochemical tests, revealing that many had low bone density (osteopenia) and vitamin D deficiency.
- The findings indicated no significant links between α-Klotho and FGF-23 levels and bone density, suggesting these proteins may not influence bone health in this age group.
Background: Osteoporosis compromises bone strength and increases the risk of fractures. Zoledronate prevents loss of bone mass and reduces the risk of fractures.
Objectives: To determine the efficacy and safety of zoledronate in postmenopausal women with osteopenia and osteoporosis.
Motor cortex transcranial direct current stimulation effects on knee osteoarthritis pain in elderly subjects with dysfunctional descending pain inhibitory system: A randomized controlled trial.
Brain Stimul
November 2021
Background: Although evidence has indicated a positive effect of transcranial direct current stimulation (tDCS) on reducing pain, few studies have focused on the elderly population with knee osteoarthritis (KOA).
Objective: To evaluate whether tDCS reduces KOA pain in elderly individuals with a dysfunctional descending pain inhibitory system (DPIS).
Methods: In a double-blind trial, individuals ≥ 60 years with KOA pain and a dysfunctional DPIS, we randomly assigned patients to receive 15 daily sessions of 2 mA tDCS over the primary motor cortex (anode) and contralateral supraorbital area (cathode) (M1-SO) for 20 min or sham tDCS.
Risk factors of pain, physical function, and health-related quality of life in elderly people with knee osteoarthritis: A cross-sectional study.
Heliyon
December 2020
Data on the precise mechanisms of the complex interactions of factors related to clinical impact of knee osteoarthritis (KOA) in the elderly population remain limited. To find predictors that explain pain intensity, physical function, and quality of life in elderly KOA subjects, we performed a cross-sectional analysis of the baseline data from a randomized trial. The trial included 104 subjects (aged ≥60) with KOA pain and dysfunctional endogenous pain-inhibitory system activity assessed by conditioned pain modulation (CPM).
View Article and Find Full Text PDFBackground: Fatigue is a frequent symptom in patients with primary Sjögren's syndrome (pSS) and can be a cause of or be associated with sleep disorders.
Objective: To assess the sleep quality of pSS patients and its relationship with fatigue and disease activity.
Design And Setting: Analytical observational study conducted at an exercise psychobiology laboratory.
Article Synopsis
- Vertebral fractures (VF) significantly impact the quality of life and health of elderly individuals, particularly those aged 80 and above, yet this demographic is under-researched.
- The study involved analyzing data from 125 elderly participants in São Paulo, Brazil, to determine the prevalence and characteristics of VFs, using various diagnostic methods and statistical analyses.
- Results revealed a high prevalence of osteoporosis and osteopenia, with 30.4% of participants diagnosed with VF through bone densitometry, and most fractures classified as severe, highlighting the need for further investigation into this vulnerable population.
Objective: To validate the Pain Assessment Checklist for Seniors with Limited Ability to Communicate - Portuguese in demented elderly and to analyze its measurement properties.
Methods: We evaluated 50 elderly with dementia, residing in a nursing home and with limited communication ability, when exposed to potentially painful situations. The tool was applied at two different moments.
Background And Objectives: Hyperleukocytosis (> 100 x 10(9)/L) is an uncommon presentation of chronic leukemias and it can present clinical symptoms of hyperviscosity syndrome. Hearing loss and blindness rarely occurs in patients with leukemia; however, it can be strong association with hyper-viscosity syndrome. The purpose of this paper is to report a case of acute hearing loss as the initial manifestation of acute leukemia and hyper-viscosity syndrome and also mainly aspects of the intensive care treatment.
View Article and Find Full Text PDFBackground And Objectives: Hepatic infarction is characterized by parenchyma ischemic necrosis involving at least two acinis. It is extremely uncommon due to the arterial and portal venous blood supply. We report a case of a patient not know to have diabetes who developed massive areas of ischemic infarcts of the liver after episode of acutely diabetes decompensated.
View Article and Find Full Text PDFBackground And Objectives: Obesity is an epidemic disease reaching more than 300 million people all over the world. Its prevalence has increased during the past few years and according to some studies its mortality in the critically ill patient seems to be much higher, especially among patients who were submitted to surgery. This study has as objective to discuss some particularities of managing obese patients in the intensive care unit after bariatric surgery.
View Article and Find Full Text PDFBackground And Objectives: Cocaine is the most commonly used illicit drug and its acute and chronic effects are related to a variety of physiological changes, mainly in the cardiovascular system. This study is a case report of a patient with cardiomyopathy related to cocaine use.
Case Report: A 19 year old men, who has been using cocaine and crack since 15 years old, was admitted to the emergency department (ED) in February 2006 with progressive dyspnea during minimal efforts and bloody expectoration.