Evaluation of sublingual microcirculation in children with dengue shock.

Objective: To report the sublingual microcirculation observed using Sidestream Dark Field imaging in two children with dengue shock.

Method: Two children, aged 9 and 10 years, were admitted to the pediatric intensive care unit with dengue shock and multiple organ dysfunction. Sublingual microcirculation was assessed in each patient on the first and second days of shock and was assessed a final time when the patients were no longer in shock (on the day prior to extubation) using Sidestream Dark Field technology.

Changing sedative infusion from propofol to midazolam improves sublingual microcirculatory perfusion in patients with septic shock.

Purpose: The goal of this study was to explore possible microcirculatory alterations by changing sedative infusion from propofol to midazolam in patients with septic shock.

Materials And Methods: Patients (n=16) were sedated with propofol during the first 24 hours after intubation, then with midazolam, following a predefined algorithm. Systemic hemodynamics, perfusion parameters, and microcirculation were assessed at 2 time points: just before stopping propofol and 30 minutes after the start of midazolam infusion.