- This study aimed to investigate the effects of SARS-CoV-2 infection on Brazilian patients with Inborn Errors of Immunity (IEI), focusing on their clinical outcomes and factors influencing the infection.
- In a multicenter study of 121 patients, the majority experienced mild or asymptomatic cases, with serious outcomes primarily linked to older age and specific comorbidities (like bronchiectasis and cardiopathy) rather than the type of IEI itself.
- Despite most infections being mild, the case fatality rate for these patients was higher than the general population, highlighting the need for targeted care in individuals with IEI.