Publications by authors named "Fernanda Ferreira Ursoli"
Article Synopsis
- - Our team developed two induced pluripotent stem cell (iPSC) lines from blood donors to produce red blood cells (RBCs) tailored for transfusions, particularly for patients with sickle cell disease, as well as for creating RBC panel reagents.
- - The iPSCs were created by reprogramming enriched erythroblast populations from the donors' blood using nonintegrative plasmid vectors, and both iPSC lines retained the unique erythrocyte antigen profiles of their respective donors.
- - These iPSC lines, which showed self-renewal and potential for hematopoietic differentiation, could lead to more efficient methods for producing donor-independent RBCs, thus meeting specific transfusion needs in the future
