Neutrophil/lymphocyte and platelet/lymphocyte ratio in seropositive women for human immunodeficiency virus (HIV) and human papillomavirus (HPV) coinfection.

This study aims to investigate the possible association between neutrophil/lymphocyte and platelet/lymphocyte ratio in women with HIV, undergoing antiretroviral treatment, with HPV coinfection. This is a cross-sectional study with HIV positive women; their biological samples were collected for laboratory tests (complete blood count) and oncotic cytology for detection of HPV DNA, by PCR-Nested (PGMY and GP primers). Viral load and CD4 and CD8 T-cells counts were obtained from medical records.

MMP-8 in Periodontal Sites of Postpartum and without-Any-Pregnancy Women.

The hypothesis that physiological changes in women can affect periodontal tissues is the subject of this study, and inflammatory markers such as matrix metalloproteinase-8 can measure susceptibility to inflammation. The study aimed to analyze MMP-8 levels in periodontal sites of postpartum women and women without a history of pregnancy, comparing health parameters and periodontal disease. This is a case-control study with 40 participants, 20 cases (women in the postpartum period) and 20 controls (women without any pregnancy), who underwent clinical periodontal examination and the collection of crevicular gingival fluid.

Klotho in Cancer: Potential Diagnostic and Prognostic Applications.

Klotho proteins, αKlotho, βKlotho, and γKlotho, exert tumor-suppressive activities via the fibroblast growth factor receptors and multiple cell-signaling pathways. There is a growing interest in Klotho proteins as potential diagnostic and prognostic biomarkers for multiple diseases. However, recent advances regarding their roles and potential applications in cancer remain disperse and require an integrated analysis.

Human Papillomavirus Modulates Matrix Metalloproteinases During Carcinogenesis: Clinical Significance and Role of Viral Oncoproteins.

Human papillomavirus (HPV) infections are associated with cervical cancer and other anogenital cancers. Despite progresses in HPV vaccination and screening, these cancers still show high incidence and mortality, requiring improved prognostic markers and tailored therapies. This review addresses the role of Matrix metalloproteinases (MMPs) in HPV-induced cancers and the modulation of MMP expression by HPV oncoproteins.

Hyperglycaemia and factors associated with dental caries in immediate postpartum women.

Dental caries and hyperglycaemia share common risk factors. The aim of this study was to identify factors associated with dental caries in women in the immediate postpartum period. It also verified whether women with hyperglycaemia presented more dental caries than those with normal glycaemia.

[Characterization of oral maxillofacial lesions resulting from physical aggression: differences between genders].

In developed countries, violence is the main cause of oral maxillofacial (OMF) injuries. In Brazil, there are scant records of such lesions. The scope of this study was to detail the OMF injuries resulting from physical aggression in a capital of the Brazilian northeast and analyze gender differences.

Association between socioeconomic factors, behavioral, general health and oral mucosa status in elderly.

This study aimed to investigate the association between socioeconomic and behavioral factors, general health, oral health, and plaque accumulation and oral mucosa condition outcomes in the elderly. This is a cross-sectional study conducted from 2004 to 2005 with 785 elderly dwellers of the city of Carlos Barbosa (RS), Brasil. We used questionnaires to collect socioeconomic, behavior and health status data.

Location of the course of the mandibular canal, anterior loop and accessory mental foramen through cone-beam computed tomography.

Purpose: This study aimed at identifying the course of the mandibular canal, the presence of anterior loop and accessory mental foramen, as well as verifying the association between these variables through the analysis of cone beam computed tomography (CBCT) exams.

Methods: CBCT images were analyzed to identify the type of mandibular canal path, classified into three types: (I) catenary; (II) progressive descending; and (III) straight. In addition, the presence of anterior loop and accessory mental foramen was analyzed.

Oral infection by Pseudomonas aeruginosa in patient with chronic kidney disease - a case report.

Chronic renal patients are more susceptible to hospital complications and infections such as urinary tract infections, peritonitis, surgery infections, and bacteremia, which are often caused by Pseudomonas aeruginosa. A case of a HIV-positive girl with chronic kidney disease and with serious oral lesions due to P. aeruginosa septic shock is presented.

Oral, systemic and socioeconomic factors associated with preterm birth.

Background: The rates of preterm births have been increasing worldwide. Complications related to preterm births are associated with increased costs of care, and have a direct impact on the health system of the countries. Therefore, it is important to address factors associated with preterm birth in order to provide prevention strategies.

Most common oral manifestations in pediatric patients HIV positive and the effect of highly active antiretroviral therapy.

This integrative literature review aims to identify the main oral lesions affecting pediatric patients with HIV, and describe the effect of highly active antiretroviral therapy (HAART) on these injuries, comparing it to antiretroviral therapy (ART). A search was conducted in PubMed and Scielo databases, following predetermined inclusion and exclusion criteria. 19 papers were selected and the main information on the prevalence and frequency of oral manifestations in HIV-positive pediatric patients and effect of therapy applied were extracted.

Relationship between Periodontal Status and Ventilator-Associated Pneumonia.

Objective: This study tested the hypothesis that a relationship exists between periodontal disease status and ventilator-associated pneumonia (VAP) in patients admitted to an intensive care unit (ICU).

Materials And Methods: The periodontal status of 60 individuals admitted to the ICU of the Dutra University Hospital was determined, including measurement of visible plaque, gingival bleeding, and clinical attachment level. Data were analyzed by Chi-square or Fisher's exact tests, unpaired Student's t-test and multivariate logistic regression.

Association between pathogens from tracheal aspirate and oral biofilm of patients on mechanical ventilation.

The aim of this study was to detect possible associations between respiratory pathogens from tracheal aspirate and oral biofilm samples in intubated patients in an intensive care unit (ICU), and to identify the most common respiratory pathogens in oral biofilm, particularly in patients that developed ventilator-associated pneumonia (VAP). Two oral biofilm samples were collected from the tongue of intubated patients (at admission and after 48 hours) and analyzed by culture with the Antibiotic Sensitivity Test. The results from the tongue biofilm samples were compared with the tracheal secretions samples.

[Oral health knowledge and practices among pregnant women using health services in São Luís, Maranhão, Brazil, 2007-2008].

Objective: to describe characteristics of oral health care during prenatal check-ups and knowledge about oral health among pregnant women using public and private health services in São Luís, Maranhão, Brazil.

Methods: this is a descriptive study of 300 women interviewed in public health services and a further 300 interviewed in private health services between August 2007 and July 2008.

Results: tooth brushing frequency was similar among users of public and private services (p=0.

Prevalence of carotid artery calcifications detected on panoramic radiographs and confirmed by Doppler ultrasonography: Their relationship with systemic conditions.

Context: Atherosclerosis affects large and medium caliber arteries by forming calcific atheromas, precursors of cerebral vascular disease. Diabetes mellitus, obesity, and hypertension are considered as risk factors of atherosclerosis. Panoramic radiographs can display images suggestive of carotid artery calcifications (CACs).

Association between chronic apical periodontitis and low-birth-weight preterm births.

Introduction: The objective of this study was to investigate the association between chronic apical periodontitis (CAP) and low-birth-weight preterm births (LBWPB).

Methods: Sixty-three women in postpartum period were included in this case-control study. The case group consisted of mothers of LBWPB infants (n = 33), and the control group was represented by mothers of newborns at term (n = 30).

The influence of hormone replacement therapy on the salivary flow of post-menopausal women.

The aim of this study is to investigate the influence of hormone therapy on salivary flow in menopausal women. It is a case-control study involving 86 post-menopausal women. The case group consisted of 47 women undergoing estroprogestative or estrogen hormone replacement therapy (HRT), and the control group consisted of 39 women who did not receive any HRT.

Periodontal status and serum biomarkers levels in haemodialysis patients.

Aim: To investigate the association between periodontal status and serum biomarkers levels in haemodialysis patients.

Methods: This cross-sectional study included 96 haemodialysis patients. The periodontal evaluation was realized using clinical attachment level (CAL), probing depth (PD), gingival bleeding index (GBI), visible plaque index (VPI) and gingival index (GI).

Association between oral DNA-HPV and genital DNA-HPV.

Background: Human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases worldwide and is observed in both men and women. The presence of the virus is often associated with benign and malignant neoplasms of the oral cavity. We wished to investigate whether HPV infection in the genitalia was associated with HPV infection in the oral mucosa.

[Periodontal disease in women in post-menopause and its relationship with osteoporosis].

Purpose: To investigate the relationship between periodontitis and osteoporosis, using a case-control study about periodontal status of postmenopausal women.

Methods: A total of 99 postmenopausal women were divided into three groups: normal bone (Gn, n=45), osteopenia (Gpenia, n=31) and osteoporosis (Gporosis, n=23). The categorization of bone mass was measured by dual energy absorptiometry with X-rays in the lumbar spine (L2 - L4), by assessing bone mineral density.

Salivary retention after application of fluoride gel using toothbrush or tray: a crossover trial.

Currently, there are no studies in the literature evaluating salivary fluoride retention after small amounts of fluoride gel are applied to children's teeth. Therefore, the objective of the present study was to compare salivary retention after gel application using a toothbrush or by traditional application with trays. In this crossover study, children with active caries (n = 10) were randomized into one of the following treatment groups: a) application of fluoride gel using a tray (control), or b) application of fluoride gel with a toothbrush (treatment).

Role of integrins in the carcinogenesis of squamous cell carcinoma of the tongue and lower lip.

Objective And Methods: This study analyzed the distribution, intensity, and pattern of immunohistochemical expression of α2β1, α3β1, and α5β1 integrins in squamous cell carcinoma (SCC) of the lower lip and tongue to identify biomarkers that reflect the clinical course of this cancer. Immunoexpression was compared considering prognostic parameters such as anatomic site, metastasis, and histologic grade of malignancy.

Results: Immunohistochemical analysis at the invasion front showed a predominance of granular cytoplasmic expression of the integrins studied.

Salivary IgA and periodontal treatment needs in diabetic patients.

Salivary IgA can serve as a first line of defense against pathogens that colonize and invade mucosal surfaces and may be protective against periodontal disease. The aim of this study was to assess salivary immunoglobulin A levels in diabetic and non-diabetic patients with different periodontal treatment needs. The Periodontal Screening & Recording (PSR) system was used to evaluate the periodontal treatment needs of 41 diabetic and 42 non-diabetic patients.