Publications by authors named "Fernanda Christoffel Gomes"
J Surg Oncol
September 2024
Article Synopsis
- The study assessed mood, anxiety, cognition, and cytokine levels in cerebrospinal fluid (CSF) among 109 participants, including cancer patients with cachexia (CC), cancer patients without cachexia (CWC), and controls.
- CC patients displayed significant levels of depression (62.96%) and anxiety, as well as notable cognitive impairments, particularly in vocabulary and attention, leading to a lower perceived quality of life compared to controls.
- Cytokine analysis revealed elevated MCP-1 levels in cancer patients, with lower levels of MIP-1β and VEGF in CC patients, indicating a correlation between mental and cognitive impairments and inflammation related to cancer and cachexia.
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