Juvenile hormone signaling in insect oogenesis.

Juvenile hormone (JH) plays a crucial role in insect reproduction, but its molecular mode of action only became clear within the last decade. We here review recent findings revealing the intricate crosstalk between JH and ecdysone signaling with nutrient sensing pathways in Drosophila melanogaster, Aedes aegypti, Tribolium castaneum and Locusta migratoria. The finding for a critical role of ecdysis triggering hormone (ETH) in both molting and ooogenesis now also highlights the importance of an integrated view of development and reproduction.

Differential gene expression underlying ovarian phenotype determination in honey bee, Apis mellifera L., caste development.

Adult honey bee queens and workers drastically differ in ovary size. This adult ovary phenotype difference becomes established during the final larval instar, when massive programmed cell death leads to the degeneration of 95-99% of the ovariole anlagen in workers. The higher juvenile hormone (JH) levels in queen larvae protect the ovaries against such degeneration.