Urban, traffic- related particles and lung tumors in urethane treated mice.

Objective: The present study was designed to evaluate the effects of urban, traffic-related, fine particulate matter (PM2.5) on mice lung tumorigenesis under controlled exposure conditions.

Methods: Four groups of female Swiss mice were treated with intraperitonial injections of urethane and saline solution.

Influence of air pollution on the incidence of respiratory tract neoplasm.

To evaluate the possible influence of air pollutants on the incidence of respiratory tract neoplasm we studied 12 São Paulo City districts where air pollution is observed. We collected data on pollutants from 1981-1990 and correlated it with the incidence of larynx and lung neoplasms in 1997. Ozone was the pollutant that best correlated with the incidence of neoplasm.