Publications by authors named "Ferhat Djerboua"

Article Synopsis
  • The study focused on creating microspheres containing Mesalazine (5-ASA) for targeted drug delivery to the colon, using an emulsion solvent evaporation method.
  • The formulation included sodium alginate and ethylcellulose as encapsulating agents and polyvinyl alcohol as an emulsifier while examining the impact of various processing parameters on the microspheres' properties.
  • Characterization methods included optical microscopy and spectroscopy, and drug release was tested in simulated gastric and intestinal fluids, with kinetic results analyzed under specific mathematical models to evaluate drug liberation.
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Chitosan/bentonite beads (CsB) composites were prepared from chitosan (Cs) and bentonite (B) and cross-linked with epichlorohydrin for removal of reactive orange 16 (RO16) and methylene blue (MB). The adsorption results have shown that the (Cs20B80), 20 % wt of (Cs) and 80 % (B), was selected as the best adsorbent for (MB) and (RO16) dyes. SEM, EDX, FTIR, BET, and pHpzc were implemented to investigate the features of Cs, B, and Cs20B80 samples.

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The aim of this study was to prepare and characterise inclusion complexes of a low water-soluble drug, mefenamic acid (MA), with β-cyclodextrin (β-CD). First, the phase solubility diagram of MA in β-CD was drawn from 0 to 21 × 10 M of β-CD concentration. A job's plot experiment was used to determine the stoichiometry of the MA:β-CD complex (2:1).

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