Publications by authors named "Fergus Evans"
Article Synopsis
- Patients in rural areas of New Zealand with acute appendicitis have worse surgical outcomes compared to those in metropolitan centers, largely due to longer wait times.
- A study analyzed data from 3533 appendicectomy cases between 2014 and 2019, revealing that rural patients faced significantly delayed treatment (20.8 hours) when transferred to urban hospitals versus quicker care (7.6 hours) at regional centers.
- Higher perforation rates (31%) and complications (20%) were observed in patients who were transferred compared to those treated in metropolitan (20% perforation, 17% complication) and regional centers (17% perforation, 10% complication).
Study Question: How does maternal cigarette smoking disturb development of the human fetal ovary?
Summary Answer: Maternal smoking increases fetal estrogen titres and dysregulates several developmental processes in the fetal ovary.
What Is Known Already: Exposure to maternal cigarette smoking during gestation reduces human fetal ovarian cell numbers, germ cell proliferation and subsequent adult fecundity.
Study Design, Size, Duration: The effects of maternal cigarette smoking on the second trimester human fetal ovary, fetal endocrine signalling and fetal chemical burden were studied.