Knocking down the expression of the molecular motors, myosin A, C and F genes in Toxoplasma gondii to decrease the parasite virulence.

Toxoplasmosis is a serious parasitic infection and novel therapeutic options are highly demanded to effectively eliminate it. In current study, Toxoplasma gondii myosin A, C and F genes were knocked down using small interference RNA (siRNA) method and the parasite survival and virulence was evaluated in vitro and in vivo. The parasites were transfected with specific siRNA, virtually designed for myosin mRNAs, and co-cultured with human foreskin fibroblasts.

Design and Fabrication of a Device for Reducing Hand Tremor in Parkinson Patients during Eating.

Background: In this paper, the method of designing a noninvasive device for eliminating hand tremors in Parkinson's patients is presented. The designed device measures the tremors of the patient's hand and implements the tremor control accordingly. Since Parkinson's disease reduces patients' abilities to perform daily activities, this device is designed as an electronic spoon.