Publications by authors named "Fereshteh Esfandiarinezhad"
Article Synopsis
- Polycystic ovarian syndrome (PCOS) involves hormonal imbalances, leading to issues like infertility, and the study focused on how the hormone dihydrotestosterone affects a specific microRNA (miR-379-5p) released from granulosa cells in developing ovarian follicles.
- Compared to non-PCOS individuals, those with PCOS show elevated testosterone, reduced exosomal miR-379-5p levels, and decreased granulosa cell growth, hinting at a link between androgens and miR-379-5p levels.
- The research found that androgens promote miR-379-5p release in early follicle stages but not later ones, suggesting that improper regulation of this process
