Treatment with troxerutin protects against cisplatin-induced kidney injury in mice.

Background: Cisplatin (CP) is a synthetic and anticancer drug, and one of the major side effects of CP is nephrotoxicity. This study was done to evaluate the renoprotective effects of troxerutin (Tro) in nephrotoxicity induced by CP in male mice.

Methods: In this experimental study, 28 male mice were divided randomly into four groups.