Publications by authors named "Fereshte Dadkhodaie"
Article Synopsis
- Researchers analyzed HLA genotypes in 99 type 1 diabetes (T1D) patients and 200 control subjects from Mali using next-generation sequencing, discovering strong associations between several HLA loci and T1D, primarily in class II genes.
- The study found that certain alleles like HLA-DRB1*03:01 and HLA-B*27:05 are linked to T1D risk, although previous findings suggested different effects, indicating potential complexities related to genetic linkages in this population.
- Amino acid-level analyses indicated that the HLA-C locus shows unique polymorphisms compared to HLA-A and HLA-B, suggesting it may have a distinct influence on T1D risk, highlighting
Full-length sequence covers the 5'-untranslated region (UTR), all introns and exons, and the 3' UTR.
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