Publications by authors named "Ferdinando Fusco"

Background: Rezūm is a novel minimally invasive surgical technique (MIST) useful for BPH patients with medium-sized prostate (30-80 cm) refractory to medical treatment. The aim of this study was to evaluate the efficacy and safety of Rezūm as a treatment option in large-sized prostates (>80 cm).

Methods: We performed a prospective, comparative, single-center study from June 2022 to June 2023, including consecutive patients undergoing surgery with the Rezūm System.

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The aim of our study is to evaluate the possible urodynamic effect of prostatic urethral lift (PUL) in patients with lower urinary tract symptoms due to benign prostatic hyperplasia. : A consecutive series of patients undergoing PUL placement were consecutively enrolled in two centers. Inclusion criteria: ≥50 years of age, benign prostatic obstruction (BPO), international prostate symptom score (IPSS) ≥ 13, prostate volume ≤ 60 mL, and no middle prostate lobe.

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Background: Multiple sclerosis (MS) is a recurrent, autoimmune, and inflammatory demyelinating chronic disease that typically manifests in young adulthood and exerts adverse effects on sexual functions.

Aim: The study evaluated the prevalence of sexual dysfunctions (SDs) and the relationship with neurological disability, depression, and lower urinary tract symptoms (LUTS) in a cohort of MS female patients, comparing these results with those of healthy women.

Methods: From January 2023 to January 2024, consecutive premenopausal female patients with MS, were recruited and the examination included urinalysis, ultrasonography and a urodynamic test according to the International Continence Society standard.

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Article Synopsis
  • * Thyroid dysfunctions, such as hyperthyroidism and hypothyroidism, can lead to various muscle issues, including weakness, fatigue, and myopathies, due to imbalances in muscle protein synthesis and degradation.
  • * Understanding the molecular mechanisms behind THs' effects on muscle can help develop strategies to manage muscle problems in individuals with thyroid diseases.
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Objectives: To evaluate the use of ureteral access sheaths (UAS) in reducing operative time and complications, as well as improving stone-free rates (SFR), while assessing their overall safety and efficiency.

Methods: Data regarding 234 patients who underwent retrograde intrarenal surgery (RIRS) for stones up to 3 cm between January 2017 and March 2020 were retrospectively analyzed. About 52.

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(1) Background: To identify a particular setting of biopsy-naïve patients in which it would be reasonable to offer only cognitive targeted prostate biopsy (PBx) with a transrectal approach. (2) Methods: We designed an observational retrospective pilot study. Patients with a prostatic specific antigen (PSA) level > 10 ng/mL, either a normal or suspicious digital rectal examination (DRE), and a lesion with a PI-RADS score ≥ 4 in the postero-medial or postero-lateral peripheral zone were included.

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Background And Objective: Symptomatic benefit and urodynamic obstruction relief represent relevant outcomes of therapies for lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). We summarized evidence from studies concurrently assessing variations in terms of symptoms severity and invasive urodynamic measures of obstruction following medical and surgical therapies for LUTS/BPH.

Methods: We performed a systematic review of PubMed, Scopus, and Web of Science in June 2023.

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Article Synopsis
  • - Bladder cancer is the 10th most common cancer worldwide, and its incidence is on the rise, with radical cystectomy and urinary diversion being standard treatments for muscle-invasive cases.
  • - Urinary diversions are classified into two main types: non-continent (like cutaneous ureterostomy and ileal conduit) and continent, which can include options that require catheterization or allow for normal voiding.
  • - The review covers the technical details of various urinary diversion techniques, providing a thorough overview of the alternatives available after radical cystectomy.
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Article Synopsis
  • Antibiotic prophylaxis (AB) reduces bacteriuria after invasive urodynamics (UDS) but does not significantly lower urinary tract infection (UTI) rates; guidelines for AB use in high-risk patients remain unclear.
  • A systematic review and expert consensus via a modified Delphi method identified key patient categories at risk for UTIs and proposed 16 statements regarding AB use.
  • The panel of 57 experts largely agreed (56.25%) on the necessity of AB for patients with neurogenic bladder and immunosuppression, while advising against AB for several other factors such as menopausal status and diabetes.
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To the Editor, Although postoperative pain associated with robot-assisted radical prostatectomy (RARP) is less than pain following the open technique, it remains a fundamental issue as it can be a significant source of discomfort for the patient and lengthen recovery times after surgery. The optimal management of pain after RARP is far from being fully elucidated and many factors have to be evaluated to choose the best analgesic approach. [.

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Article Synopsis
  • - The study analyzed the outcomes of radical prostatectomy (RP) in men who have previously undergone surgery for lower urinary tract symptoms due to benign prostatic enlargement (LUTS/BPE) by reviewing 25 studies involving over 11,000 patients.
  • - Results showed that these patients had a higher rate of positive surgical margins and poorer urinary continence outcomes at both 3 months and 1 year compared to those without prior LUTS/BPE surgery.
  • - While there was no significant difference in biochemical recurrence rates, erectile function recovery was also notably lower in patients with a history of LUTS/BPE surgery.
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Introduction: Normal sexual activity is an important determinant of quality of life. Unfortunately, several chronic health disorders are associated with an impaired sexual function.

Objective: To provide coverage of the current literature on prevalence and pathophysiology of sexual dysfunction in patients with gastrointestinal and liver disorders.

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The aim of this study was to evaluate the ability of Google Assistant, Alexa, and Siri to recognize and answer questions about male sexual health. Each VA was tested on a smart speaker: Alexa on Amazon Echo Dot 4th Gen., Google Assistant on Google Home Mini, and Siri on Apple HomePod.

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Objectives: To assess YouTube™ videos' quality on prostate checks, especially on the digital rectal exam (DRE), and to investigate if they can inform patients correctly and eradicate their beliefs and myths.

Methods: A search using as keywords "digital rectal exam for prostate cancer" was performed on the YouTubeTM platform. We selected the first 100 videos.

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Introduction: Although stapled anastomoses have been widely evaluated in the context of the elective surgery, few reports compared manual with stapled anastomoses in patients undergoing emergency surgery. The aim of this study is to compare the outcome of hand-sewn end-to-end anastomoses with stapled side-to-side and stapled end-to-side anastomoses in patients undergoing small bowel resection for acute mesenteric ischemia secondary to intestinal obstruction.

Methods: From January 2015 to June 2021 all the hemodynamically stable patients undergoing emergency surgery with small bowel resection for intestinal obstruction were enrolled in this study.

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It is now well established that the urothelium does not act as a passive barrier but contributes to bladder homeostasis by releasing several signaling molecules in response to physiological and chemical stimuli. Here, we investigated the potential contribution of the hydrogen sulfide (HS) pathway in regulating human urothelium function in β adrenoceptor-mediated relaxation. The relaxant effect of BRL 37344 (0.

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The management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, management, and outcomes of these patients. Twenty-seven studies involving 252 patients were identified.

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Introduction: Several urological conditions that share an impairment of tissue oxygenation can benefit from hyperbaric oxygen therapy; limited evidence is available of its impact on patients undergoing male-to-female gender affirmation surgery.

Aim: To evaluate the efficacy and safety of hyperbaric oxygen therapy as adjuvant treatment for surgical site infections in patients undergoing male-to-female gender affirmation surgery.

Methods: This research was conducted as an observational retrospective study.

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The management of patients with oligometastatic urothelial carcinoma (UC) represents an evolving field in uro-oncology, and the role of metastasis-directed therapies, including metastasectomy and metastasis-directed radiation therapy (MDRT), is gaining increasing attention. Herein, we summarize available evidence about the role of MDRT with consolidative intent in oligometastatic UC patients. A systematic review was performed in December 2021.

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