The present study aimed to investigate the preventive effects of methanol fraction from leaf extract (MECA), associated with its phytochemical content, on CCl-induced hepatic toxicity in adult rats. In the controls, CCl induced an increase of serum biochemical parameters and triggered oxidative stress in the liver. MECA caused significant reductions in CCl-elevated levels of hepatic markers, total cholesterol, triglycerides, and low-density lipoprotein and increased the level of high-density lipoprotein compared to the CCl group.
View Article and Find Full Text PDFThe inner bark of cinnamon () is widely used as a spice. Cinnamon plants are also a valuable source of essential oil used for medicinal purposes. The present study aimed to investigate the composition and in vitro antioxidant activity of essential oil of bark (CvEO) and its protective effects in vivo on CCl-induced hepatic and renal toxicity in rats.
View Article and Find Full Text PDFThe present study aimed to evaluate the performance effect of aqueous extract of (AERO) against the kidney toxicity induced by CCl in mice. The results showed that the renal damage induced by CCl was associated with a rise in oxidative stress monitored by a significant increase of TBARS and PCO levels (+89% and +136% respectively, < .001) and a significant decrease of GSH level (-68%, < .
View Article and Find Full Text PDFThe aerial part of Clematis flammula (Ranunculaceae) has been traditionally used in the treatment of skin diseases including mycotic infection in the Tunisian traditional medicine. The study was undertaken to extract and determine the essential oil chemical composition of Clematis flammula aerial parts and to assess the potential of anemonin in wound healing on mechanically wounded wistar rats. The essential oil was obtained by hydrodistillation and analyzed by GC-MS.
View Article and Find Full Text PDFFermented milk is known to possess potent antioxidant activity. The present study was undertaken to assess the preventive effect of fermented camel milk (FCM) prepared using lactococcus lactis subsp. cremoris against CCl4 induced kidney damage in mice.
View Article and Find Full Text PDFContext: Kombucha (KT) is claimed to have various beneficial effects on human health, but there is very little scientific evidence available in the literature.
Objective: The present study investigates the effects of Camellia sinensis (GT) Linn. (Theaceae) and KT, two natural drinks, on cholesterol and antioxidant status using a hypercholesterolemia rat model.