Publications by authors named "Fenna Visser"
Objective: To compare the association of the severity categories of the 2001-National Institutes of Health (NIH), the 2018-NIH and the 2019-Jensen bronchopulmonary dysplasia (BPD) definitions with neurodevelopmental and respiratory outcomes at 2 and 5 years' corrected age (CA), and several BPD risk factors.
Design: Single-centre historical cohort study with retrospective data collection.
Setting: Infants born between 2009 and 2015 at the Amsterdam University Medical Centers, location Amsterdam Medical Center.
Introduction: The objective of this study was to identify risk factors for neurodevelopmental impairment (NDI) at 2- and 5-years corrected age (CA) in a cohort of preterm infants with established bronchopulmonary dysplasia (BPD).
Methods: This single-center retrospective cohort study included infants born between 2009 and 2016 at a gestational age (GA) <30 weeks with moderate or severe BPD at 36 weeks' postmenstrual age. Perinatal characteristics, (social) demographics, and comorbidities were collected from the electronic patient records.
Article Synopsis
- The study aimed to investigate how the severity of bronchopulmonary dysplasia (BPD) affects the risk of neurodevelopmental impairment (NDI) at ages 2 and 5 years, and whether this relationship changes over time.
- Involving 790 infants born before 30 weeks of gestation, the findings showed that those with varying degrees of BPD had a significantly higher risk of NDI compared to infants without BPD, with a marked increase in NDI risk from age 2 to age 5.
- The research concluded that greater BPD severity correlates with higher NDI risk at both ages, and while the incidence of NDI increased from 2 to 5 years,
Unlabelled: To establish the validity of biochemical markers of metabolic bone disease (MBD) in preterm infants.
Conclusion: There is insufficient evidence that any of the frequently used serum measurements are valid biochemical markers of MBD in preterm infants. Increased urinary calcium concentration may be a valid biochemical marker, but more research is necessary to confirm this.