Simvastatin encapsulated in exosomes can enhance its inhibition of relapse after orthodontic tooth movement.

Introduction: Relapse after orthodontic treatment is a major clinical issue in the dental field. Studies indicate that simvastatin may, to some extent, decrease the rate and magnitude of relapse status. Recent evidence demonstrated that exosome-based drug delivery has a broad prospect of clinical application.

The bridging and normal dimensions of sella turcica in Yemeni individuals.

Objective: This study aimed to evaluate and compare sizes, shapes and bridging of the sella turcica (ST) in Yemeni individuals with different skeletal patterns, genders, and ages, and to assess the association between the linear dimension of ST and gender, age, or skeletal patterns. The standard anatomical structure of ST among Yemeni subjects is still unknown and this study can be considered as the first reference regarding ST of Yemeni individuals.

Materials And Methods: Cephalogram images for 234 subjects (167 females and 67 males) were traced and classified for groups by gender, age, and dentofacial skeletal patterns.

Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.

Fluorosis is a common disease characterized by disruptions in bone metabolism and enamel development. The production of reactive oxygen species is thought to play an important role in fluorosis. Gastrodin (4-hydroxybenzylalcohol4-O-beta-D-glucopyranoside) has been reported to have antioxidative activity, and so here we examined whether gastrodin has protective effects against oxidative stress and bone tissue toxicity in rats with fluorosis.

Association of congenital missing of maxillary lateral incisors with cervical vertebral body fusions and/or atlas posterior arch deficiency.

To evaluate the association between congenital missing of maxillary lateral incisor (MLI) with cervical vertebral body fusions, posterior arch deficiency, and both anomalies. A total of 64 subjects (24 males and 40 females; mean age 16 ± 4.5 years) were detected to have congenital missing of MLI and selected as a study group.

Effect of repeated laser surface treatments on shear bond strength between zirconia and veneering ceramic.

Statement Of Problem: Delamination failure may occur between ceramic frameworks and veneering ceramics, shortening the lifetime of fixed dental prostheses in load-bearing areas.

Purpose: The purpose of this in vitro study was to compare the effect of different repeating CO laser treatment methods and conventional approaches on the shear bond strength of zirconia frameworks and veneering ceramics.

Material And Methods: Zirconia disks (N=110) were prepared and divided into 5 groups: milling without surface treatment (group M), airborne-particle abrasion (group APA), single laser treatment (group LX1), 2 laser treatments (group LX2), and 3 laser treatments (group LX3).

Morphology, Incidence of Bridging, Dimensions of Sella Turcica, and Cephalometric Standards in Three Different Racial Groups.

This study aims to assess the morphological appearance, incidence of bridging, linear dimensions of sella turcica and establish cephalometric standards in Bosnian, Chinese and Nepalese subjects. This retrospective study examined digital standardized lateral cephalograms of 540 subjects, which consisted of 116 females and 64 males with an age range of 8 to 28 years. The sella morphology, bridging, and size were analyzed on the lateral cephalograms.

The impact of laser scanning on zirconia coating and shear bond strength using veneer ceramic material.

Laser scanning is one of the methods that can be used for surface treatments of zirconia. Application of the laser to the surface of zirconia has diverse effects, depending on the type of laser. A carbon dioxide (CO) laser has high irradiation power and can alter the surface properties.

Effects of different surface treatments on the shear bond strength of veneering ceramic materials to zirconia.

Purpose: To evaluate and compare the effect of different materials and techniques on the shear bond strength of veneering ceramic materials to zirconia.

Materials And Methods: 136 sintered zirconia cubes were prepared and randomly divided into four study groups according to corresponding methods of surface treatment and materials: GLN (grinding followed by laser scanning using Noritake Cerabien ZR), SLN (sandblasting followed by laser scanning using Noritake Cerabien ZR), GLV (grinding followed by laser scanning using VITA VM 9), and SLV (sandblasting followed by laser scanning using VITA VM 9). Spraying technique was performed to coat the core.

Morphology, incidence of bridging, and dimensions of sella turcica in different racial groups.

Objectives: This study was performed to assess the morphological appearance, incidence of bridging, and linear dimensions of the sella turcica (ST) in Bosnian and Iraqi subjects, and to identify associations of sex, age, and racial group with the size of the ST.

Methods: The digital standardised lateral cephalograms of 360 Bosnian and Iraqi patients (116 female, 64 male; age range 8-28 years) were retrospectively analysed. The following ST-related parameters were analysed on the lateral cephalograms: sella morphology, sella bridging, and sella size.

Comparison of perceptions on the dental aesthetics of different malocclusions between orthodontists and schoolchildren.

Objectives: To compare perceptions on dental aesthetics of various malocclusions between schoolchildren and orthodontists with an orthodontic assessment of treatment needs.

Methods: The prospective study was conducted between late March-December in 2017. A total of 32 orthodontists practicing in Shenyang, China and 116 schoolchildren (59 boys and 57 girls) aged 10-12 years (average= 11±0.

Effect of orthodontic force on the expression of PI3K, Akt, and P70S6 K in the human periodontal ligament during orthodontic loading.

The mammalian target of rapamycin (mTOR) is an atypical serine/threonine protein kinases involved in the regulation of cell growth, proliferation, and differentiation through the PI3K/Akt/mTOR/P70S6 K signalling pathway. P70S6 K as a downstream molecule of mTOR is activated by phosphorylation and subsequently promotes the synthesis of ribosomal and translational proteins. In this study, we investigated the role of PI3K, Akt, and P70S6 K in human periodontal tissue remodelling during orthodontic loading.

Factors controlling crystallization of miserite glass-ceramic.

Objective: The purpose of this study was to investigate a range of variables affecting the synthesis of a miserite glass-ceramic (GC).

Methods: Miserite glass was synthesized by the melt quench technique. The crystallization kinetics of the glass were determined using Differential Thermal Analysis (DTA).