A nonvolatile magnon field effect transistor at room temperature.

Information industry is one of the major drivers of the world economy. Its rapid growth, however, leads to severe heat problem which strongly hinders further development. This calls for a non-charge-based technology.

[Clinical and genetic analysis of a patient with Neuronal intranuclear inclusion body disease characterized by cortical enhancement in the posterior brain region].

Objective: To explore the clinical, imaging, and genetic characteristics of an adult patient with sporadic Neuronal intranuclear inclusion disease (NIID).

Methods: A patient who had visited the First People's Hospital of Chenzhou on August 6, 2023 was selected as the study subject. Results of clinical examination, neuroimaging, and genetic testing were retrospectively analyzed along with a literature review.

Direct Measurement of Negative Capacitance in Ferroelectric/Semiconductor Heterostructures.

Negative capacitance (NC) is now an attractive research topic owing to its potential applications. For better integration, investigation about the phenomenon and mechanism of NC in ferroelectric materials on semiconductor substrates is important. In this work, ferroelectric BaTiO (BTO) films are deposited on the low-resistance Si(100) substrates to constitute Pt/BTO/p-Si/Pt samples with the metal/ferroelectric/semiconductor/metal (MFSM) structure, on which NC are directly measured at low frequencies with a large DC bias.

Effects of schedule exercise therapy on chronic insomnia.

Schedule exercise therapy (SET) is a novel nonpharmacological intervention for the treatment of chronic insomnia disorder (CID). The aim of this study was to explore the effects of SET on CID. Methods: One hundred and eighteen CID were recruited and randomized into medication (MED) or medication combined with SET (MSET) groups.

Structural Distortion-Modulated Magnetic and Dielectric Properties in Nonstoichiometric YbTiO Pyrochlore.

Rare-earth titanate pyrochlores have attracted considerable attention for their unique magnetic frustration. Among those compounds, YbTiO, a candidate for quantum spin ice, has been extensively studied in its magnetic ground state. However, works on its dielectric property and structure-property relationship lag far more behind.

Controllable Distribution and Reversible Migration of Charges in BiFeO-Based Films on Si Substrates.

In ferroelectric-based integrated devices, there are usually buffer layers between ferroelectric films and semiconductor substrates. Here, BiFeO ( = 95, 100, and 105) (BFO) films are prepared directly on n-Si substrates by the sol-gel method, and the variation of the hysteresis loops with Bi content and heat treatment is investigated. With the help of the dielectric measurement and the composition analysis, a PN heterojunction is believed to exist at the BFO/Si interface.

Design of Two-Dimensional Multiferroics with Direct Polarization-Magnetization Coupling.

The recent discovery of two-dimensional (2D) ferromagnetism in van der Waals materials has opened the door to the control of 2D magnetism by means of electric field. Here we demonstrate the magnetization reversal through switching polarization in a designed 2D multiferroic oxide by combining group theory analysis and first-principles calculation. We show that ferroelectricity can be induced by a specific octahedral rotation in a perovskite bilayer.

Case report: narcolepsy type 2 due to temporal lobe glioma.

Rationale: The orexin projection system includes the lateral hypothalamus, reticular activating structure, and ventrolateral preoptic nucleus, and this system is related to the pathogenesis of narcolepsy. Here, we report a case of narcolepsy type 2 caused by hippocampal glioma of the right temporal lobe.

Patient Concerns: A 44-year-old male farmer complained of excessive daytime sleepiness (EDS) over the past 3 months and more.

Ectopic expression of a R2R3 MYB transcription factor of dove tree (Davidia involucrata) aggravates seed abortion in Arabidopsis thaliana.

Serious seed abortion of dove tree (Davidia involucrate Baill.) is one of the critical factors leading to the low fecundity of this species. Seed abortion is a complicated process and various factors have been verified to synergistically determine the fate of seeds.

Hole Transfer Promoted by a Viscosity Additive in an All-Polymer Photovoltaic Blend.

Viscosity modifiers are widely applied to improve the mechanical compliance of organic optoelectronic devices. However, the effect of the viscosity additives on the charge dynamics remains poorly understood. Here, we report the observation of markedly different effects of a high-viscosity polymeric additive on the electron- and hole-transfer dynamics in all-polymer organic photovoltaic blends.

Dynamics and manipulation of ferroelectric domain walls in bismuth ferrite thin films.

Ferroelectric domain walls differ from domains not only in their crystalline and discrete symmetry, but also in their electronic, magnetic, and mechanical properties. Although domain walls provide a degree of freedom to regulate the physical properties at the nanoscale, the relatively lower controllability prevents their practical applications in nano-devices. In this work, with the advantages of 3D domain configuration detection based on piezoresponse force microscopy, we find that the mobility of three types of domain walls (tail-to-tail, head-to-tail, head-to-head) in (001) BiFeO films varies with the applied electrical field.

Effect of electroacupuncture on relieving central post-stroke pain by inhibiting autophagy in the hippocampus.

Introduction: To explore the underlying mechanism of electroacupuncture (EA) treatment on central post-stroke pain (CPSP), and provide basic evidence for the EA treatment on CPSP.

Methods: Firstly, 40 male SD rats were successfully established with a model of CPSP, under the intervention of different EA frequencies (2 Hz and 15 Hz) and fluoxetine (5 ml/kg and 0.4 mg/ml), whose brain tissue was then removed for paraffin-embedded sectioning; secondly, LPS induced the primary brain cells in the hippocampus to cause inflammation model which were added NS398 (inhibitor of COX-2) and DKK-1 (inhibitor of β-catenin) later.

Upregulation of the lncRNA MEG3 improves cognitive impairment, alleviates neuronal damage, and inhibits activation of astrocytes in hippocampus tissues in Alzheimer's disease through inactivating the PI3K/Akt signaling pathway.

Objective: The purpose of this study was to elucidate the expression of the long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) in rats with Alzheimer's disease (AD) and to explore its potential mechanisms.

Methods: An AD rat model was induced by microinjection of Aβ . On the first day after successful modeling, pcDNA3.

LncRNA SNHG12 as a potent autophagy inducer exerts neuroprotective effects against cerebral ischemia/reperfusion injury.

Long-non-coding RNA small nucleolar RNA host gene 12(SNHG12) was reported to be highly up-regulated in brain microvascular endothelium after cerebral ischemia. Autophagy has been shown to have protective effects against cerebral ischemic insults. However, molecular mechanisms of SNHG12 in regulating autophagy during cerebral ischemia/reperfusion (I/R) injury remain unclear.

Lipopolysaccharide Stimulated the Migration of NIH3T3 Cells Through a Positive Feedback Between β-Catenin and COX-2.

How β-catenin/COX-2 contribute to inflammation-induced fibroblasts migration remains poorly understood. Therefore, in this study, lipopolysaccharide (LPS) was used as a stimulus to accelerate the migration of NIH3T3 cells, which mimicked the tissue repair process. LPS treatment increased the cell migration in concentration-and time-dependent manner.

Upregulation of miR-496 decreases cerebral ischemia/reperfusion injury by negatively regulating BCL2L14.

Neurological functions were seriously impaired by cerebral ischemia-reperfusion (I/R) injury following ischemic stroke and its molecular mechanism is still not fully understood. MicroRNA-496 (miR-496) has been reported to be deregulated in several diseases but it still remains unknown about the function of miR-496 in cerebral I/R injury. Here, Middle cerebral artery occlusion/reperfusion (MCAO/R) was performed to induce cerebral I/R injury in rats.

The exchange bias behavior of BiFeO nanoparticles with natural core-shell structure.

The surface and interface effects of small antiferromagnetic nanostructures are important on the modulation of their magnetic properties. In this report, temperature and particle size dependent magnetic exchange bias effect was investigated in BiFeO (BFO) nanoparticles that possess natural core-shell structure. Nonmonotonic variation of exchange bias field, interesting surface spin-glass state and improved exchange bias training effect are only obtained in 18 nm BFO particles.

Toward Understanding Non-coding RNA Roles in Intracranial Aneurysms and Subarachnoid Hemorrhage.

Subarachnoid hemorrhage (SAH) is a common and frequently life-threatening cerebrovascular disease, which is mostly related with a ruptured intracranial aneurysm. Its complications include rebleeding, early brain injury, cerebral vasospasm, delayed cerebral ischemia, chronic hydrocephalus, and also non neurological problems. Non-coding RNAs (ncRNAs), comprising of microRNAs (miRNAs), small interfering RNAs (siRNAs) and long non-coding RNAs (lncRNAs), play an important role in intracranial aneurysms and SAH.

Improved magnetic and magnetoelectric properties in BaFeO nanostructures.

The structural, magnetic and magnetoelectric properties were investigated for sol-gel prepared BaFeO nanorods and plate-like nanoparticles. Based on comparative experiments with bulk ceramics, it is found that larger structural distortion is present in nanostructures, which could cause the enhancement of magnetocrystalline anisotropy and the off-center displacement of Fe ions, and thus result in improved magnetic and magnetoelectric properties in BaFeO plate-like nanoparticles. Meanwhile, the local (Fe-Fe) dipoles, which usually appear during a high temperature sintering process, can also contribute to the negative magnetoelectric effect of BaFeO nanorods and a large room temperature magnetodielectric coefficient of about -13% is observed at 10 Hz and 9 kOe.

Development of functionalized hollow microporous organic capsules encapsulating morphine - an in vitro and in vivo study.

Microporous organic capsules with hollow interiors have received enormous attention due to their unusual encapsulation efficiency to confine chemicals within their hollow cavities and prompted controlled release by circumventing their ripening or poisoning. To this end, herein, we report the design and synthesis of carboxylic group functionalized hollow microporous organic capsules (HMOCs) using a facile emulsion polymerization technique that show extraordinary high encapsulation efficiency (up to 98%) of morphine·HCl and its promising prolonged release. The functionalized HMOCs are found to release the drug at a rate which is proportional to the amount of drug remaining in its interior.

Induced core-shell structure and the electric properties of (KNa)LiNbSbO ceramics.

The relationship among dielectric anomaly, ferroelectric response, defects, and microstructures was established for (KNa)LiNbSbO (x = 0.04, 0.00, -0.

miRNA profiling in autism spectrum disorder in China.

Autism spectrum disorder (ASD) is a clinically complex and heterogeneous disorder. It is characterized by impaired social abilities, disordered language, isolated areas of interest, and repetitive behaviors. Evidence suggested that the neuropathology of ASD is widely distributed, involving epigenetic regulation in the brain.

Spectrum reconstruction using relative-deviation-based kernel regression in temporally and spatially modulated Fourier transform imaging spectrometer.

During the temporally and spatially modulated Fourier transform imaging spectrometer push-broom scanning process, the motion state of the spectrometer platform can vary. Thus, the target interferogram obtained from the image sequence deviates from the ideal interferogram obtained using high platform stability. The recovered target spectrum will not reflect the true target characteristics.

Studying the Polarization Switching in Polycrystalline BiFeO3 Films by 2D Piezoresponse Force Microscopy.

For rhombohedral multiferroelectrics, non-180° ferroelectric domain switching may induce ferroelastic and/or (anti-)ferromagnetic effect. So the determination and control of ferroelectric domain switching angles is crucial for nonvolatile information storage and exchange-coupled magnetoelectric devices. We try to study the intrinsic characters of polarization switching in BiFeO3 by introducing a special data processing method to determine the switching angle from 2D PFM (Piezoresponse Force Microscopy) images of randomly oriented samples.

Hepatic encephalopathy coexists with acquired chronic hepatocerebral degeneration.

Hyperkinetic extrapyramidal syndrome is the typical clinical characteristic of acquired hepatocerebral degeneration (AHD), but is usually not observed with hepatic encephalopathy (HE). We present a case of AHD coexisting with HE. Both conditions were secondary to liver cirrhosis and hepatitis C virus infection.