Risk Factors Affecting Cognitive Impairment of the Elderly Aged 65 and Over: A Cross-Sectional Study.

Objectives: Elderly population with cognitive impairment has been accelerating in China. This study aimed to explore the relationship between each risk factor and each cognitive domain to provide evidence for risk prevention of controlling impaired cognitive function in elderly.

Methods: This cross-sectional study analyzed the cognitive status of the elderly aged 65 and above in three communities in Shizhong District of Jinan City.

A Systematic Review of Body Fluids Biomarkers Associated With Early Neurological Deterioration Following Acute Ischemic Stroke.

Biomarkers are objectively measured biological properties of normal and pathological processes. Early neurological deterioration (END) refers to the deterioration of neurological function in a short time after the onset of acute ischemic stroke (AIS) and is associated with adverse outcomes. Although multiple biomarkers have been found to predict END, there are currently no suitable biomarkers to be applied in routine stroke care.

Erratum to "Spinocerebellar ataxia type 40: A case report and literature review".

[This corrects the article DOI: 10.1515/tnsci-2020-0190.].

Spinocerebellar ataxia type 40: A case report and literature review.

Spinocerebellar ataxias (SCAs) are a group of neurodegenerative diseases with ataxia as the main clinical manifestation. The phenotypes, gene mutations, and involved sites of different subtypes show a high degree of heterogeneity. The incidence of SCA varies greatly among different subtypes and the case of SCA40 is extremely rare.

Transcriptome Sequencing Identifies Potential Biomarker for White Matter Lesions Diagnosis in the Hypertension Population.

Hypertension is confirmed to be one of the major risk factors of leukoaraiosis (LA). However, the pathogenesis of LA is not completely understood and there is no reliable indicator for the early diagnosis of LA in the hypertensive population. This study was designed to explore the potential biomarker for LA diagnosis in patients with hypertension.

Sex Differences in Risk Factors for Transient Ischemic Attack in a Chinese Population.

This study aimed to collect and evaluate basic information of a stroke screening population in eastern China and to compare distribution differences in risk factors between males and females in a transient ischemic attack (TIA) population. A standardization of the risk factors for stroke was performed according to an implementation plan of stroke in a high-risk population screening and intervention project in Shandong Province. Of the 231,289 residents, 8,603 patients with a previous TIA were identified and risk factors in this cohort were analyzed for sex differences.

[Observation on pathological changes of the medial aspect of the first metatarsal head of hallux valgus].

Objective: To observe pathological characteristic of bone and soft tissue of the medial aspect of the first metatarsal head in order to investigate the pathogenesis of hallux valgus.

Methods: One hundred and twenty-three patients with hallux valgus (235 feet) were obtained from August 2003 to December 2004 in our department. The bone and soft tissue of the medial aspect of the first metatarsal head were taken out from the incision.

[Change of gene expression pattern and regulation of SFK on the change in early stage after hemitransection of the spinal cord in rat].

Objective: To investigate the changes of gene expression in early stage of hemitransection of spinal cord and the regulatory effects of the traditional Chinese mixture Suifukang (SFK) on these changes.

Methods: Eighty-six adult male SD rats were randomly divided into 3 groups: Suifukang group (Group S, n = 31, administered with SFK 3 days before the hemitransection at the dose of 2.5 g crude drugs/100 kg body weight QD and then 4 h and 8 h after hemitransection), model group (Group M, n = 45, administered with normal saline in the manner as in Group S), and normal control group (Group N, n = 10, without any treatment).

[Study on effect of suifukang in regulating the change of free radical after hemitransected spinal cord injury].

Objective: To explore the regulatory effect of Suifukang (SFK), a compound Chinese patent drug on the change of free radical in tissue of spinal cord and blood caused by experimental spinal injury.

Methods: Seventy male adult SD rats were randomly divided into 4 groups, the SFK group (n = 20), the hormone group (n = 20), the control group (n = 20) and the normal group (n = 10). Rats in the former three groups were made into the right hemitransected spinal cord (T12) injury.