IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery.

Objective: This research sought to assess the predictive potential of the inflammation-immunity-nutrition score (IINS) and the high-sensitivity C-reactive protein-albumin-lymphocyte (CALLY) index in individuals with NSCLC post-surgery.

Methods: The study enrolled 506 patients with NSCLC undergoing R0 resection at the First Affiliated Hospital of Xi'an Jiaotong University. The training cohort was analyzed utilizing X-tile software to identify the ideal threshold values for categorizing high-sensitivity C-reactive protein, albumin, lymphocyte count, and the CALLY index.

Renewable symmetric supercapacitors assembled with lignin nanoparticles-based thin film electrolyte and carbon aerogel electrodes.

Lignin as a natural biopolymer is becoming increasingly in demand due to its eco-friendly properties, while lignin-based electrolyte with high conductivity and reliable durability for applications in supercapacitors is still challenging. Herein, a facile method to prepare lignin nanoparticles (LNPs)-based solid electrolyte thin film (LF) was proposed through chemical cross-linking reaction. The fabricated LF exhibited a distinctive spongy porous structure with the ionic conductivity of 3.

The dual role of SUSD2 in cancer development.

Sushi domain-containing protein 2 (SUSD2, also known as the complement control protein domain) is a representative and vital protein in the SUSD protein family involved in many physiological and pathological processes beyond complement regulation. Cancer is one of the leading causes of death worldwide. The complex role of SUSD2 in tumorigenesis and cancer progression has raised increasing concerns.

FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.

FBXO32, a member of the F-box protein family, is known to play both oncogenic and tumor-suppressive roles in different cancers. However, the functions and the molecular mechanisms regulated by FBXO32 in lung adenocarcinoma (LUAD) remain unclear. Here, we report that FBXO32 is overexpressed in LUAD compared with normal lung tissues, and high expression of FBXO32 correlates with poor prognosis in LUAD patients.

Reversal Effect of Phosphorus on Catalytic Performances of Supported Nickel Catalysts in Reductive Amination of 1,6-Hexanediol.

The reductive amination of 1,6-hexanediol with ammonia is one of the most promising green routes for synthesis of 1,6-hexanediamine. Herein, we developed a phosphorous modified Ni catalyst of Ni-P/AlO. It presented satisfactory improved selectivity to 1,6-hexanediamine in the reductive amination of 1,6-hexanediol compared to the Ni/AlO catalyst.

VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.

Triple-negative breast cancer (TNBC) has long been considered a major clinical challenge due to its aggressive behavior and poor prognosis. Cancer stem cells (CSCs) are known as the main cells responsible for tumor origination, progression, recurrence and metastasis. Here, we report that M2-type tumor-associated macrophages (TAMs) contribute to cancer stemness in TNBC cells via the secretion of VEGFA.

COL: a pipeline for identifying putatively functional back-splicing.

Circular RNAs (circRNAs) are a class of generally non-coding RNAs produced by back- splicing. Although the vast majority of circRNAs are likely to be products of splicing error and thereby confer no benefits to organisms, a small number of circRNAs have been found to be functional. Identifying other functional circRNAs from the sea of mostly non-functional circRNAs is an important but difficult task.

A Practical Multi-Stage Grasp Detection Method for Kinova Robot in Stacked Environments.

Grasp detection takes on a critical significance for the robot. However, detecting object positions and corresponding grasp positions in a stacked environment can be quite difficult for a robot. Based on this practical problem, in order to achieve more accurate object position detection and grasp position detection, a new method called MMD (Multi-stage network for multi-object grasp detection algorithm) is proposed in this paper.

Comprehensive analysis of the prognostic value and immune infiltration of family members in gastric cancer.

Background: Fibroblast growth factor receptors () modulate numerous cellular processes in tumor cells and tumor microenvironment. However, the effect of on tumor prognosis and tumor-infiltrating lymphocytes in gastric cancer (GC) remains controversial.

Methods: The expression of four different types of was analyzed GEPIA, TCGA-STAD, and GTEX databases and our 27 pairs of GC tumor samples and the adjacent normal tissue.

Enhancing the scalability of distance-based link prediction algorithms in recommender systems through similarity selection.

Slope One algorithm and its descendants measure user-score distance and use the statistical score distance between users to predict unknown ratings, as opposed to the typical collaborative filtering algorithm that uses similarity for neighbor selection and prediction. Compared to collaborative filtering systems that select only similar neighbors, algorithms based on user-score distance typically include all possible related users in the process, which needs more computation time and requires more memory. To improve the scalability and accuracy of distance-based recommendation algorithm, we provide a user-item link prediction approach that combines user distance measurement with similarity-based user selection.

LHPP suppresses colorectal cancer cell migration and invasion in vitro and in vivo by inhibiting Smad3 phosphorylation in the TGF-β pathway.

The roles of phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) in tumorigenesis have been recently proven in hepatocellular carcinoma (HCC), cervical, pancreatic, bladder, and thyroid cancers. Previous research demonstrated that LHPP repressed cell proliferation and growth by inactivating the phosphatidylinositol 3-kinase/AKT signaling pathway in vitro and in vivo. However, the functions and potential mechanisms of LHPP as a tumor suppressor in colorectal cancer (CRC) metastasis are still unknown.

Identification of core genes and clinical outcomes in tumors originated from endoderm (gastric cancer and lung carcinoma) via bioinformatics analysis.

During last decade, bioinformatics analysis has provided an effective way to study the relationship between various genes and biological processes. In this study, we aimed to identify potential core candidate genes and underlying mechanisms of progression of lung and gastric carcinomas which both originated from endoderm. The expression profiles, GSE54129 (gastric carcinoma) and GSE27262 (lung carcinoma), were collected from GEO database.

Laparoscopic Duodenal Switch Versus Roux-en-Y Gastric Bypass at a High-Volume Community Hospital: a Retrospective Cohort Study from a Rural Setting.

Background: The classic duodenal switch (DS) represents a minority of bariatric procedures due to its high complexity and potential for complications.

Methods: A retrospective chart review was conducted on 100 laparoscopic DS cases from 2014 to 2018 at an accredited program in a rural community hospital and compared to 100 laparoscopic Roux-en-Y gastric bypasses (RYGB). Primary outcomes were 30-day morbidity and mortality.

Direct Synthesis of Polyurea Thermoplastics from CO and Diamines.

The transformation of CO into polymeric materials is an important and hot research topic from the viewpoint of renewable resources and environmental effects. Herein, a series of polyureas have been synthesized by polycondensation from CO with diamines of 1,12-diaminododecane (DAD) and/or 4,7,10-trioxa-1,13-tridecanediamine (TTD). The properties of polyureas synthesized were characterized by FTIR, H NMR, C NMR, XRD, DSC, TGA, and DMA.

Numerical Investigation of the Effect of Additional Pulmonary Blood Flow on Patient-Specific Bilateral Bidirectional Glenn Hemodynamics.

The effect of additional pulmonary blood flow (APBF) on the hemodynamics of bilateral bidirectional Glenn (BBDG) connection was marginally discussed in previous studies. This study assessed this effect using patient-specific numerical simulation. A 15-year-old female patient who underwent BBDG was enrolled in this study.

Highly selective Pt/ordered mesoporous TiO2-SiO2 catalysts for hydrogenation of cinnamaldehyde: The promoting role of Ti(2.).

A highly selective and stable catalyst based on Pt nanoparticles confined in Mesoporous TiO2-SiO2 frameworks were prepared and employed for selective hydrogenation of cinnamaldehyde to cinnamyl alcohol. The as-prepared Pt/MesoTiO2-SiO2-M catalyst displayed excellent selectivity to cinnamyl alcohol (around 91%) at nearly complete conversion. Ti(2+) and stronger metal-support interaction (SMSI) played key roles on the adsorption behavior of cinnamaldehyde and activation of CO bonds.

Selective hydrogenation of o-chloronitrobenzene over anatase-ferric oxides supported Ir nanocomposite catalyst.

The catalytic performance of Ir/TiO2-FeOx, an Ir/TiO2 catalyst modified with FeOx, was investigated for the hydrogenation of o-chloronitrobenzene, FeOx was found to promote both the activity and selectivity significantly. The initial reaction rate of Ir/TiO2-FeOx(10) nanocomposite catalyst was four times as high as that of Ir/TiO2 catalyst. Especially, the accumulation of intermediates was prohibited and finally 100% selectivity to o-chloroaniline was obtained at 100% conversion.

Photocatalytic reduction of o-chloronitrobenzene under visible light irradiation over CdS quantum dot sensitized TiO2.

The photocatalytic activity of CdS/P25 hybrid catalysts was studied under visible-light irradiation. The CdS quantum dots sensitized P25 (CdS QDs-P25) showed extremely enhanced activity in the reduction of o-chloronitrobenzene (o-CNB) by comparing to CdS-P25 prepared by the direct deposition-precipitation method in the presence of HCOOH. The synergistic effects between CdS QDs and P25 were beneficial for the separation of photogenerated carriers in space and thus the combination of photoelectrons and holes was prevented, and the CdS QDs could provide more photocharges than CdS due to the particle size effect.

Embedding NiCo2O4 nanoparticles into a 3DHPC assisted by CO2-expanded ethanol: a potential lithium-ion battery anode with high performance.

A high-performance anode material, NiCo2O4/3DHPC composite, for lithium-ion batteries was developed through direct nanoparticles nucleation on a three-dimensional hierarchical porous carbon (3DHPC) matrix and cation substitution of spinel Co3O4 nanoparticles. It was synthesized via a supercritical carbon dioxide (scCO2) expanded ethanol solution-assisted deposition method combined with a subsequent heat-treatment process. The NiCo2O4 nanoparticles were uniformly embedded into the porous carbon matrix and efficiently avoided free-growth in solution or aggregation in the pores even at a high content of 55.

The Pt-enriched PtNi alloy surface and its excellent catalytic performance in hydrolytic hydrogenation of cellulose.

Ni-based catalysts are currently a subject of intense research in the hydrolytic hydrogenation of cellulose. We previously reported that Ni/ZSM-5 catalyst gave high yield of hexitols. However, Ni-based catalysts suffered fast deactivation in hot-compressed water.

Supercritical carbon dioxide assisted deposition of Fe(3)O(4) nanoparticles on hierarchical porous carbon and their lithium-storage performance.

A composite of highly dispersed Fe3 O4 nanoparticles (NPs) anchored in three-dimensional hierarchical porous carbon networks (Fe3 O4 /3DHPC) as an anode material for lithium-ion batteries (LIBs) was prepared by means of a deposition technique assisted by a supercritical carbon dioxide (scCO2 )-expanded ethanol solution. The as-synthesized Fe3 O4 /3DHPC composite exhibits a bimodal porous 3D architecture with mutually connected 3.7 nm mesopores defined in the macroporous wall on which a layer of small and uniform Fe3 O4 NPs was closely coated.

Supported polyethylene glycol stabilized platinum nanoparticles for chemoselective hydrogenation of halonitrobenzenes in scCO2.

Polyethylene glycol stabilized platinum nanoparticles were immobilized on solid supports such as γ-Al2O3, SBA-15, TiO2 and active carbon, forming supported polyethylene glycol stabilized platinum nanoparticles (SPPNs). In the hydrogenation of p-chloronitrobenzene (p-CNB) in supercritical carbon dioxide (scCO2), the SPPN showed high selectivity to p-chloroaniline (>99.3%) in the whole range of conversion.

Assembling metal oxide nanocrystals into dense, hollow, porous nanoparticles for lithium-ion and lithium-oxygen battery application.

New dense hollow porous (DHP) metal oxide nanoparticles that are smaller than 100 nm and composed of Co3O4, FeOx, NiO and MnOx were prepared by densely assembling metal oxide nanocrystals based on the hard-template method using a carbon colloid as a sacrificial core. These nanoparticles are quite different from the traditional particles as their hollow interior originates from the stacking of nanocrystals rather than a spherical shell. The DHP nanoparticles preserve the intriguing properties of nanocrystals and possess desirable surface area and pore volume that enhance the active surface, which ultimately benefits applications such as lithium-ion batteries.

Trace amounts of water-induced distinct growth behaviors of NiO nanostructures on graphene in CO2-expanded ethanol and their applications in lithium-ion batteries.

In this work, we have developed a new method to grow NiO nanomaterials on the surface of graphene nanosheets (GNSs). The morphologies of NiO nanomaterials grown on GNSs could be tailored by trace amounts of water introduced into the mixed solvents of CO2-expanded ethanol (CE). Small and uniform Ni-salt nanoparticles (Ni-salt-NPs) were grown on the surface of graphene oxide (GO) through the decomposition of nickel nitrate directly in CE.