Association between serum uric acid levels and peripheral artery disease in Chinese adults with hypertension.

Background: Higher serum uric acid (SUA) can cause gout, which is principally characterized by arthritis due to monosodium urate crystal deposition in the lower extremities. High levels of SUA have been linked to endothelial dysfunction, oxidative stress, and inflammation, all of which are involved in the pathogenesis of peripheral artery disease(PAD). To date, the relationship between SUA levels and PAD is still poorly understood.

Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults.

The aim of this study was to assess the relationship between basal metabolic rate (BMR) and all-cause mortality in southern Chinese adults. We prospectively examined the relationship between BMR and all-cause mortality in 12,608 Southern Chinese adults with age ≥ 35 years who participated in the National Key R&D Program from 2013-2014 to 2019-2020. Cox proportional hazard models were used to examine the association between BMR and all-cause mortality.

Prospective Study of Serum Uric Acid Levels and First Stroke Events in Chinese Adults With Hypertension.

We investigated the association between serum uric acid (SUA) levels and the risk of the first stroke in Chinese adults with hypertension. A total of 11, 841 hypertensive patients were selected from the Chinese Hypertension Registry for analysis. The relationship between SUA levels and first stroke was determined using multivariable Cox proportional hazards regression, smoothing curve fitting, and Kaplan-Meier survival curve analysis.

Does body mass index or waist-hip ratio correlate with arterial stiffness based on brachial-ankle pulse wave velocity in Chinese rural adults with hypertension?

Background: The relationship between obesity indices and arterial stiffness (AS) has not been fully discovered nor has it been studied in depth in large hypertensive patient populations. The aim of this study was to explore the association between body mass index (BMI) and waist-hip ratio (WHR) levels and AS based on brachial-ankle pulse wave velocity (baPWV) in Chinese rural adults with hypertension.

Methods: This cross-sectional study analyzed 5049 Chinese rural adults with essential hypertension.

Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review).

Cardiac fibrosis is a hallmark of cardiac remodeling associated with nearly all forms of heart disease. Clinically, no effective therapeutic drugs aim to inhibit cardiac fibrosis, owing to the complex etiological heterogeneity and pathogenesis of this disease. A two-in-one protein structure, a ubiquitous expression profile and unique biophysical characteristics enable the involvement of transient receptor potential melastatin-subfamily member 7 (TRPM7) in the pathogenesis and development of fibrosis-related cardiac diseases, such as heart failure (HF), cardiomyopathies, arrhythmia and hyperaldosteronism.

Chemical constituents from and their chemotaxonomic significance.

Phytochemical investigation of the roots of Fr. Schmidt. ex Miq.

Research on a novel chitosan microsphere/scaffold system by double crosslinkers.

RhBMP-2 has shown great promise for the reconstruction of teeth segmental bone defects due to its osteoinductive properties. But the application of rhBMP-2 is limited by its weak drug controled release. It is usually loaded in a Chitosan Microspheres (CMs) delivery system with excess single cross-linker and then removed before practice.

[Study on genetic polymorphism of Platycodon grandiflorum based on barcoding of ITS2].

Objective: ITS2 of DNA barcoding was used to study genetic polymorphism of Platycodon grandiflorum.

Method: Total genomic DNA was isolated from P. grandiflorum.

Protective effects of oxymatrine on experimental diabetic nephropathy.

Diabetic nephropathy, one of the most common and serious vascular complications of both type 1 and type 2 diabetes mellitus, has become a major contributor of end-stage renal failure. The aims of this study were to investigate the effects and possible underlying action mechanism(s) of oxymatrine on renal damage in diabetic rats. Diabetes was induced in male Sprague-Dawley rats by administering a high-fat diet and an intraperitoneal 30 mg/kg streptozotocin injection.